Evidence mapPaperPMID 41675263Full record

ReviewFrontiers in nephrology2025

The potential of neutrophil gelatinase-associated lipocalin in management of acute kidney injury and peritoneal dialysis-related peritonitis: a narrative review.

Xiao Fu, Yiting Shu, Yun Zhang

Abstract readReview
In one paragraph

Review in Frontiers in nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiao FuGlobal Medical Information and Education, Fresenius Medical Care Asia Pacific Limited, Hong Kong, Hong Kong SAR, China.
Yiting ShuGlobal Medical Information and Education, Fresenius Medical Care Asia Pacific Limited, Hong Kong, Hong Kong SAR, China.
Yun ZhangGlobal Medical Information and Education, Fresenius Medical Care Asia Pacific Limited, Hong Kong, Hong Kong SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker extensively studied in multiple diseases. While its application in chronic kidney disease (CKD) and kidney transplant patients is relatively limited, NGAL has shown significant promise in the early detection and diagnosis of acute kidney injury (AKI), which may improve more timely management and potentially better clinical outcomes. In addition, NGAL has demonstrated promising utility in identifying peritoneal dialysis-related peritonitis (PDRP) and monitoring the treatment response. This review aims to provide an in-depth overview of the available research findings of NGAL in the management of AKI and PDRP, having these two conditions discussed together is particularly important for nephrologists who manage both conditions, especially to explore the potential of more specific NGAL forms, such as monomer NGAL and homodimer NGAL, to enhance early diagnosis and effective management of AKI and PDRP.

Indexed as

acute kidney injurybiomarkerearly detectionmolecular formneutrophil gelatinase-associated lipocalinperitoneal dialysis-related peritonitispoint-of-care testing

Identifiers

PMID41675263
PMCPMC12886388

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.