Evidence map›Paper›PMID 41676000›Full record

ArticleBio-protocol2026

Simple and Rapid Model to Generate Differentiated Endometrial Floating Organoids.

Adriana Bajetto, Alessandra Pattarozzi, Alessandro Corsaro, Beatrice F Tremonti, Stefano Thellung, Federica Barbieri, Tullio Florio

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Article in Bio-protocol, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adriana BajettoSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.
Alessandra PattarozziSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.
Alessandro CorsaroSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.
Beatrice F TremontiSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.
Stefano ThellungSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.
Federica BarbieriSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.
Tullio FlorioSection of Pharmacology, Department of Internal Medicine, University of Genova, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, the use of 3D cultures (organoids) is considered a valuable experimental tool to model physiological and pathological conditions of organs and tissues. Organoids, retaining cellular heterogeneity with the presence of stem, progenitor, and differentiated cells, allow the faithful in vitro reproduction of structures resembling the original tissue. In this context, the growth of endometrial organoids allows the generation of 3D cultures characterized by a hollow lumen, secretory activity, and apicobasal polarity and displaying phenotypical modification in response to hormone stimulation. However, a limitation in currently used models is the absence of stromal cells in their structure; as a result, they miss epithelial-stromal interactions, which are crucial in endometrial physiology. We developed a novel 3D model to generate endometrial organoids grown in floating Matrigel

Indexed as

Endometrial organoidsEndometrium differentiationEpithelial cellsIn vitro 3D cultureStromal cells

Identifiers

PMID41676000
PMCPMC12887873

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.