Evidence map›Paper›PMID 41677648›Full record

ArticleCells2026

Targeting the c-Met/VEGFR Pathway to Boost

Jennifer Huang, Quinn Kaurich, Md Sazzad Hassan, Urs von Holzen, Niranjan Awasthi

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer HuangDepartment of Surgery, Indiana University School of Medicine, South Bend, IN 46617, USA.
Quinn KaurichDepartment of Surgery, Indiana University School of Medicine, South Bend, IN 46617, USA.ORCID 0000-0002-4974-898X
Md Sazzad HassanDepartment of Surgery, Indiana University School of Medicine, South Bend, IN 46617, USA.ORCID 0000-0001-6309-9616
Urs von HolzenDepartment of Surgery, Indiana University School of Medicine, South Bend, IN 46617, USA.
Niranjan AwasthiDepartment of Surgery, Indiana University School of Medicine, South Bend, IN 46617, USA.

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI David W Clapp · 1999 to 2026
$59.3M
Indiana University School of Medicine 23-817-16NCI NIH HHS P30 CA082709
6 · The paper itself

Abstract

Combination chemotherapy regimens are commonly employed to treat advanced gastric adenocarcinoma (GAC), yet median survival remains less than one year.

Indexed as

AlbuminsPaclitaxelProto-Oncogene Proteins c-metReceptors, Vascular Endothelial Growth FactorSignal TransductionStomach NeoplasmsAnimalsCell Line, TumorFemaleHumansMiceMice, Inbred NODMice, SCIDXenograft Model Antitumor Assays130-nm albumin-bound paclitaxelAlbuminsPaclitaxelProto-Oncogene Proteins c-metReceptors, Vascular Endothelial Growth Factorc-Metgastric cancermerestinibnab-paclitaxelVEGFR

Identifiers

PMID41677648
PMCPMC12897347

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.