Evidence map›Paper›PMID 41677657›Full record

ReviewCells2026

Targeting Amyloid Beta Aggregation and Neuroinflammation in Alzheimer's Disease: Advances and Future Directions.

Ioanna Dagla, Faidon Gkikas, Evagelos Gikas, Anthony Tsarbopoulos

Abstract readReview
In one paragraph

Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ioanna DaglaBioanalytical Laboratory, GAIA Research Center, The National Natural History Museum Goulandris, 145 62, Athens, Greece.ORCID 0000-0003-1387-3532
Faidon GkikasBioanalytical Laboratory, GAIA Research Center, The National Natural History Museum Goulandris, 145 62, Athens, Greece.
Evagelos GikasLaboratory of Analytical Chemistry, Faculty of Chemistry, National and Kapodistrian University of Athens, 157 71 Athens, Greece.ORCID 0000-0002-0107-9991
Anthony TsarbopoulosBioanalytical Laboratory, GAIA Research Center, The National Natural History Museum Goulandris, 145 62, Athens, Greece.ORCID 0000-0002-6843-5575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly. Among the diverse pathological features of AD, amyloid beta (Aβ) aggregation and neuroinflammation are recognized as central and interlinked mechanisms driving disease progression. This review focuses specifically on these two processes and highlights current pharmacological limitations in modifying disease pathology. Natural products such as curcumin, resveratrol,

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesNeuroinflammatory DiseasesAnimalsBlood-Brain BarrierDrug Delivery SystemsHumansNeuroprotective AgentsAmyloid beta-PeptidesNeuroprotective AgentsAlzheimer’s diseaseamyloid-β aggregationcannabidiolCrocus sativus L.curcuminEGCGinflammasomenanomedicinenanoparticlesnatural productsneuroinflammationresveratrol

Identifiers

PMID41677657
PMCPMC12897309

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.