Evidence map›Paper›PMID 41677909›Full record

ArticleCalcified tissue international2026

Different Effects of Tacrolimus on Osseointegration and Bone Mass in Normal Bone Mineral Density and Ovariectomized Rats.

Zhou-Shan Tao, Wanshu Zhou

Abstract read
PubMed Publisher
In one paragraph

Article in Calcified tissue international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhou-Shan TaoFirst Affiliated Hospital of Wannan Medical College, Yijishan Hospital, No. 2, Zhe Shan Xi Road, Wuhu, 241001, Anhui, People's Republic of China. taozhoushan1990@126.com.
Wanshu ZhouSecond Affiliated Hospital of Wannan Medical College, No. 10 Kangfu Road, Jinghu District, Wuhu City, 241000, Anhui, People's Republic of China. 1025066337@qq.com.

Funding

Anhui University Natural Science Key Project 2025AHGXZK30237Health Research Project of Anhui Province AHWJ2023A20550Key project, young and middle-aged project of Wannan Medical College WK2024ZZD29, WK2023ZQNZ62
6 · The paper itself

Abstract

This study aims to investigate the effects of tacrolimus (TAC) on the osseointegration of titanium rods in ovariectomized (OVX) and Sham-operated (Sham) rats. Additionally, it seeks to explore the role of TAC in the differentiation of osteoblasts and osteoclasts under high Oxidative Stress. Firstly, the effect of TAC on osseointegration in both OVX and sham-operated rats was examined. Subsequently, TAC was utilized to modulate the differentiation of MC3T3-E1 cells and RAW264.7 cells under H

Indexed as

Bone and BonesBone DensityOsseointegrationTacrolimusAnimalsCell DifferentiationFemaleImmunosuppressive AgentsMiceOsteoblastsOsteoclastsOsteogenesisOvariectomyOxidative StressRatsRats, Sprague-DawleyImmunosuppressive AgentsTacrolimusInflammatory factorsOsseointegrationOsteoporosisOxidative stressTacrolimus

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.