ArticleFunctional & integrative genomics2026
Ectopic expression of the sesuvium portulacastrum L. SpHDZ39 and SpHDZ41 enhances growth and cadmium tolerance in Arabidopsis.
Article in Functional & integrative genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
The homeodomain-leucine zippers (HDZs) function as key regulators to regulating plant growth, development, and responses to environmental stress. Its functions have been extensively investigated in many plant species, while the HDZs family in Sesuvium portulacastrum L. remains poorly characterized and the roles of SpHDZs have not been explored. Here, we identified 46 SpHDZs in the S. portulacastrum genome and classified them into four subfamilies. The SpHDZs are unevenly distributed across 21 chromosomes. We systematically predicted their physicochemical properties, including gene and protein structures, isoelectric points, hydrophobicity, stability, secondary and tertiary structures, and subcellular localization. Gene duplication analysis revealed that all identified duplications resulted from whole-genome or segmental events, with most gene pairs exhibited signs of purifying selection. Promoter analysis indicated the presence of numerous cis-elements associated with stress signaling and development. Expression profiling of cadmium, copper, and salt treatment identified a subset of SpHDZs that responsive to these stresses, of which SpHDZ39 and SpHDZ41 showing significant downregulation in roots under cadmium treatment. Subcellular localization and yeast one-hybrid assays confirmed that both SpHDZ39 and SpHDZ41 function as transcription factors. Ectopic expression of SpHDZ39 and SpHDZ41 in Arabidopsis thaliana promoted root growth and increased biomass accumulation under cadmium treatment. These results provide an insight into the functional roles of SpHDZs in halophytic species and offer promising candidate genes for improving cadmium tolerance in crops through genetic engineering.
Indexed as
Identifiers
41677928What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.