Evidence mapPaperPMID 41677930Full record

ArticleEuropean journal of nutrition2026

Dietary phosphorus intake and its association with metabolic syndrome and its components: a cross-sectional analysis of the UK national diet and nutrition survey (NDNS).

R E Khoury, O Obeid, M Malla, A Avery, S Welham

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Article in European journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

R E KhouryDivision of Food, Nutrition & Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
O ObeidDepartment of Nutrition and Food Sciences, American University of Beirut, Beirut, Lebanon.
M MallaDepartment of Epidemiology and Biostatistics, American University of Beirut, Beirut, Lebanon.
A AveryDivision of Food, Nutrition & Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
S WelhamDivision of Food, Nutrition & Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK. Simon.welham@nottingham.ac.uk.ORCID http://orcid.org/0000-0002-9409-1032

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePhosphorus plays a critical role in carbohydrate and energy metabolism, yet its relationship with metabolic health outcomes remains underexplored. This study aimed to investigate the association between dietary phosphorus intake and the prevalence of metabolic syndrome (MetS), as well as individual MetS components, using data from the UK National Diet and Nutrition Survey.

methodsData from adults aged 19 years and older were analyzed. Dietary phosphorus intake was assessed using four-day food diaries. MetS was defined based on established clinical criteria. Logistic regression models evaluated the association between phosphorus intake quintiles and MetS occurrence, adjusting for demographic, anthropometric, dietary, and lifestyle factors. Associations between phosphorus intake and individual MetS components were examined based on both total phosphorus intake and phosphorus density.

resultsIndividuals in the highest phosphorus intake quintile (> 1509 mg/day) exhibited a 56% lower risk of MetS compared to those in the lowest quintile (OR = 0.44, p  = 0.0004). Higher phosphorus intake was associated with a decrease of 10.4 mg/dl in triglyceride levels from quintile 1 to quintile 5 (mean ± SD: 118.6 ± 87.5 vs. 108.2 ± 61.7, p =  0.002), as well as a 2.1 mmHg reduction in diastolic blood pressure (mean ± SD: 74.6 ± 11.1 vs. 72.5 ± 10.7, p = 0.001). Additionally, modest variations in HDL cholesterol and waist circumference were observed.

conclusionHigher dietary phosphorus intake was associated with a lower risk of MetS and beneficial differences in certain MetS components, supporting a potential protective role of phosphorus in metabolic health.

Indexed as

DietMetabolic SyndromeNutrition SurveysPhosphorus, DietaryAdultAgedBlood PressureCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsTriglyceridesUnited KingdomPhosphorus, DietaryTriglyceridesBlood pressureCross-sectional analysisDyslipidemiaGlycemiaMetabolic syndromeNational diet and nutrition surveyPhosphorus

Identifiers

PMID41677930
PMCPMC12901275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.