Evidence map›Paper›PMID 41678053›Full record

SynthesisJournal of epidemiology and global health2026

Mortality among Children Aged 1-59 Months in India: Evidence from a Systematic Review and Meta-Analysis (2009-2024).

Melissa Glenda Lewis, M A Lone, Oindrila Roy Chowdhury, Pramit Ghosh, Rounik Talukdar, N Sreekumanran Nair, Santasabuj Das, Suman Kanungo

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of epidemiology and global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Quality of Medical Certification of Cause of Death in a City of Assam.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melissa Glenda LewisICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India.
M A LoneICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India.
Oindrila Roy ChowdhuryICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India.
Pramit GhoshICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India.
Rounik TalukdarICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India.
N Sreekumanran NairJawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Santasabuj DasICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India.
Suman KanungoICMR, National Institute for Research in Bacterial Infections (NIRBI), Kolkata, India. sumankanungo@gmail.com.

Funding

Indian Council of Medical Research INTR-IG-2024-01-0020
6 · The paper itself

Abstract

backgroundMortality among Indian children aged 1–59 months remains a concern, yet evidence arises from hospital and community settings that reflect different populations and metrics. A setting-specific synthesis is needed to clarify mortality trends, causes, and associated factors.

methodsWe reviewed observational studies (2009–2024) on deaths, causes, or risk factors among children aged 1–59 months. Two reviewers independently extracted data. Hospital and community studies were analyzed separately, using setting-specific mortality definitions. Random-effects GLM models pooled mortality and risk factors. Cause-of-death distributions and trends were synthesized only for hospital studies due to limited community data.

findingsSixty-seven studies were included: 50 hospital-based, 11 community-based, and six case-control. The pooled in-hospital mortality was 8.1%, with substantial heterogeneity (0.1%-65%); largely reflecting cohorts restricted to critically ill children. Pneumonia (38%), congenital anomalies (32%) and central nervous system infections (23%), accounted for most clinically ascertained deaths. Deaths declined over time (2.4%) particularly during the pre-COVID period; while post-COVID trends were imprecise; a regional decline (3%) was detected only in northern India. Community mortality was highly heterogeneous, with a pooled estimate of 3.3% and data were insufficient for trend analysis. Female sex and lack of immunization were significantly associated with in hospital mortality, while no significant risk factors were identified in community analyses.

conclusionIndia achieved meaningful reductions in child mortality, although recent trends remain uncertain following the COVID-19 period. Persistent heterogeneity across settings and sex differences in hospital-based mortality underscore the need for strengthened community surveillance and standardized reporting to sustain and accelerate national gains.

Indexed as

Child MortalityHospital MortalityInfant MortalityCause of DeathChild, PreschoolFemaleHumansIndiaInfantMaleRisk FactorsChildrenCommunity-based studiesHospital admissionsIndiaMeta-analysisMortalityPostnatal period

Identifiers

PMID41678053
PMCPMC12963583

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.