Evidence map›Paper›PMID 41678708›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2026

Associations of unmet dental care needs due to cost with incident cardiovascular disease and dementia: a prospective study in the All of Us cohort.

Mabeline Velez, Peter T Buto, Anna M Pederson, Jennifer Weuve, Audrey R Murchland, Jingxuan Wang, M Maria Glymour, Kendra D Sims

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mabeline VelezDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0003-1172-7873
Peter T ButoDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.
Anna M PedersonDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.
Jennifer WeuveDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0003-0922-0256
Audrey R MurchlandDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.
Jingxuan WangDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States.
M Maria GlymourDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0001-9644-3081
Kendra D SimsDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States.

Funding

Building an unbiased pooled cohort for the study of lifecourse social and vascular determinants of Alzheimer's Disease and Related DisordersR01AG072681 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GLYMOUR, MEDELLENA MARIA, ZEKI AL HAZZOURI, ADINA · 2021 to 2025
$4.0M
Community Empowerment, Vascular Risk, and ADRD Disparities: Translating Research to Public PolicyK99AG083121 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SIMS, KENDRA D · 2023 to 2024
$243k
NIA NIH HHS K99 AG083121NIA NIH HHS L60 AG089791NIH HHS K99AG083121NIH HHS L60AG089791NIH HHS R01AG072681
6 · The paper itself

Abstract

backgroundPoor oral health among older adults may contribute to cardiovascular and dementia risk via systemic inflammation and cardiometabolic comorbidities. Financial constraints are a major driver of unmet dental care needs for older individuals. This study investigates whether having dental care needs that were unmet due to cost is associated with subsequent incidence of cardiovascular disease (CVD) or dementia among adults aged 55 and older.

methodsParticipants in the All of Us cohort (N = 98 787) who responded to a survey question on dental care needs that were unmet due to cost were followed up to 5.3 years via electronic health records for onset of myocardial infarction (MI), stroke, heart failure (HF), or dementia. We estimated outcome-specific hazard ratios (HRs), using Cox proportional-hazards models, adjusting for demographic, behavioral, and clinical covariates.

resultsAfter adjustment for demographic factors, individuals who reported unmet dental needs due to cost had relatively higher incidence of HF (HR = 1.45; 95% CI, 1.30-1.63), MI (HR = 1.37; 95% CI, 1.17-1.61), stroke (HR = 1.45; 95% CI, 1.24-1.70), and dementia (HR = 1.37; 95% CI, 1.05-1.76). These associations were attenuated after further adjusting for socioeconomic, behavioral, and clinical factors. We did not observe differences by gender, racial and ethnic identity, or periodontitis diagnosis. The estimated population attributable fraction suggested that eliminating financial barriers to dental care could prevent 2%-4% of each outcome among older adults.

conclusionFinancial barriers to dental care may be an important determinant of CVD and dementia among aging populations.

Indexed as

Cardiovascular DiseasesDementiaDental CareHealth Services Needs and DemandAgedFemaleHumansIncidenceMaleMiddle AgedProspective StudiesUnited StatesCardiovascular diseaseDementiaEpidemiologyOral health

Identifiers

PMID41678708
PMCPMC13016879

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.