Evidence map›Paper›PMID 41678735›Full record

ReviewBriefings in bioinformatics2026

Pathways, outputs and impact of NIH-supported bioinformatics and genomics graduate trainees in Africa.

Daudi Jjingo, Andrew Walakira, Suhaila Hashim, Cisse Cheickna, Ronald Galiwango, Caleb Kibet, Florence N Kivunike, Gerald Mboowa, Fredrick Elishama Kakembo, Babajide Ayodele and 57 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Briefings in bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

67 authors.

Daudi JjingoThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.ORCID 0000-0003-1685-9234
Andrew WalakiraThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Suhaila HashimDepartment of Biochemistry and Biotechnology, Kilifi Ganze Rd, Pwani University, Kilifi, Kenya.
Cisse CheicknaThe African Center of Excellence in Bioinformatics and Data-Intensive Science, University of Sciences, Techniques and Technologies of Bamako, J287+PM5, Bamako, Mali.
Ronald GaliwangoThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.ORCID 0000-0002-5962-151X
Caleb KibetMartin Lüscher Emerging Infectious Diseases Laboratory, International Centre of Insect Physiology and Ecology, Ndemi Rd, Nairobi, Kenya.
Florence N KivunikeThe Department of Information Technology, College of Computing and Information Sciences , Hill Rd, Makerere University, Uganda.
Gerald MboowaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.ORCID 0000-0001-8445-9414
Fredrick Elishama KakemboThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Babajide AyodeleCovenant University Bioinformatics Research, Department of Computer and Information Sciences, 10 Idiroko Road, Covenant University, Ota, Ogun, 112233, Nigeria.
Jean-Baka Domelevo EntfellnerBiosciences Eastern and Central Africa, International Livestock Research Institute Hub, P.O. Box 30709, Nairobi 00100, Kenya.
Santie de VilliersDepartment of Biochemistry and Biotechnology, Kilifi Ganze Rd, Pwani University, Kilifi, Kenya.
Karen WambuiMartin Lüscher Emerging Infectious Diseases Laboratory, International Centre of Insect Physiology and Ecology, Ndemi Rd, Nairobi, Kenya.
Segun FatumoPrecision Healthcare University Research Institute, Queen Mary University of London, Mile End Rd, London, United Kingdom.
Tinashe ChikoworeChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Ave, Boston 02115, United States.
John MukisaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Alfred SsekagiriThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.ORCID 0000-0002-6549-3550
Nicholas BbosaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Julius MulindwaThe Department of Biochemistry, College of Natural Sciences, Makerere University, P. O. Box 7062, Kampala, Uganda.
Samuel KyobeDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, Upper Mulago Hill Rd, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Mike NsubugaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Grace KebirungiThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Eric KatagiryaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, Upper Mulago Hill Rd, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Savannah MwesigwaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, Upper Mulago Hill Rd, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.ORCID 0000-0001-5466-2315
Ibra LujumbaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Rogers KamulegeyaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, Upper Mulago Hill Rd, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Samuel KirimundaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, Upper Mulago Hill Rd, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Stephen KanyereziThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Shahiid KiyagaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Ivan SserwaddaThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Davis KiberuThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Bernard S BagayaThe Infectious Diseases Institute, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Julius OkwirThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Patricia NabisubiThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Grace NabakoozaOak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States, Assigned to Centers for Disease Control and Prevention, P.O. Box 117, Atlanta, GA  United States.
Mugume Twinamatsiko AtwineThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Ricard SserunjogiThe African Center of Excellence in Bioinformatics and Data-Intensive Sciences, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Rolanda JuliusComputational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Mariam QuiñonesOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Meghan McCarthyOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Phillip CruzOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Karlynn NobleOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Christopher J WhalenOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Darrell HurtOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Maria Y GiovanniOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Michael TartakovskyOffice of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Deogratius SsemwangaMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Nakiwogo Rd, PO Box 49, Entebbe, Uganda.ORCID 0000-0001-9675-4234
John M KitayimbwaUganda Christian University, Bishop Tucker Rd, Mukono, Uganda.
Steven J ReynoldsDivision of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Christopher C WhalenDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, United States.
Andrew KambuguThe Infectious Diseases Institute, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Neil A HanchardDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, United States.
Li JianSchool of Public Health and Tropical Medicine, Tulane University, New Orleans, New Orleans, LA 70112, United States.
Peter Amoako-YirenkyiDepartment of Economics and Statistics, Garden City University College, Kenyasi, Ghana.
Graeme MardonDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, United States.
I King JordanSchool of Biological Sciences, Georgia Institute of Technology, 10 Ferst Dr NW, Atlanta, GA 30332, United States.
Samson Pandam SalifuDepartment of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Mamadou WeleThe African Center of Excellence in Bioinformatics and Data-Intensive Science, University of Sciences, Techniques and Technologies of Bamako, J287+PM5, Bamako, Mali.
Ezekiel AdebiyiThe Infectious Diseases Institute, Hall Lane, Makerere University, Central, P.O BOX 22418, Kampala, Uganda.
Jeffrey G ShafferSchool of Public Health and Tropical Medicine, Tulane University, 1440 Canal St, New Orleans, LA 70112, United States.
Seydou DoumbiaFaculty of Medicine and Odontostomatology, University of Sciences Techniques and Technologies of Bamako, M2C3+HW9, Bamako, Mali.
David Patrick KateeteDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, Upper Mulago Hill Rd, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Michelle SkeltonComputational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Nicola MulderComputational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-4905-0941
Jonathan K KayondoEntomology Division, Uganda Virus Research Institute, 51/59 Nakiwogo Rd, Entebbe, Uganda.
Daniel MasigaInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya.
H3Africa Consortium

Funding

Emory/Georgia TB Research Advancement Center (TRAC)P30AI168386 · EMORY UNIVERSITY · 2025 to 2025
$972k
West Africa Center of Excellence for Data Science Research EducationUE5TW012526 · UNIV OF SCIENCES, TECH & TECH OF BAMAKO · 2025 to 2025
$200k
FIC NIH HHS U2R TW010673FIC NIH HHS UE5 TW012526NIAID NIH HHS P30 AI168386
6 · The paper itself

Abstract

Global biomedical and health research is increasingly relying on genomic and computational approaches, largely driven by the increasing volumes of nucleic acid sequencing. Concurrently, epidemiological studies and clinical records are generating enormous amounts of data amenable to disease modeling, machine learning, and artificial intelligence techniques. Bioinformatics and data science expertise is therefore essential for improved population health. Accordingly, in 2012, the US National Institutes of Health (NIH) in partnership with the Wellcome Trust, and with support from the African Society for Human Genetics, initiated the H3Africa (Human Heredity and Health in Africa) consortium. One of its key goals was to build capacity among African scientists to lead research on genetic and environmental contributors to health and disease across the continent. In 2017, the NIH provided funding to support the establishment of four graduate bioinformatics training programs across five African universities. Over seven years, these programs enrolled multiple trainees (n > 270), with >110 earning Master's degrees and >20 completing PhDs in Bioinformatics. It is thus timely to evaluate the outcomes and impact of these programs, particularly regarding graduation rates, career trajectories, and the institutions and research domains their alumni are serving. We also assess employment outcomes and the nature of the research they are enabling (n > 110 peer-reviewed articles). We additionally include the progress and outputs of the programs' instructors, which were partially enabled by program resources, networks, and trainees. Overall, this review paints valuable insights into the pioneering role of NIH extramural support in shaping Africa's biomedical research landscape.

Indexed as

Computational BiologyEducation, GraduateGenomicsNational Institutes of Health (U.S.)AfricaBiomedical ResearchHumansUnited StatesAfricabioinformaticsgenomicsgraduate traineespost-graduation pathways

Identifiers

PMID41678735
PMCPMC12900072

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.