Evidence map›Paper›PMID 41680289›Full record

ArticleScientific reports2026

Chitosan and polycaprolactone blended PDMS coatings improve biocompatibility of magnetic elastomers.

Joanna Mystkowska, Dawid Łysik, Anna Czerniakiewicz, Ewelina Piktel, Piotr Deptuła, Robert Bucki, Dariusz Perkowski, Jakub Augustyniak, Arkadiusz Mystkowski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joanna MystkowskaInstitute of Biomedical Engineering, Bialystok University of Technology, Wiejska 45C, Bialystok, 15-351, Poland. j.mystkowska@pb.edu.pl.
Dawid ŁysikInstitute of Biomedical Engineering, Bialystok University of Technology, Wiejska 45C, Bialystok, 15-351, Poland.
Anna CzerniakiewiczInstitute of Biomedical Engineering, Bialystok University of Technology, Wiejska 45C, Bialystok, 15-351, Poland.
Ewelina PiktelIndependent Laboratory of Nanomedicine, Medical University of Bialystok, Bialystok, Poland.
Piotr DeptułaDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, Poland.
Robert BuckiDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, Poland.
Dariusz PerkowskiInstitute of Mechanical Engineering, Bialystok University of Technology, Wiejska 45C, Bialystok, Poland.
Jakub AugustyniakInstitute of Mechanical Engineering, Bialystok University of Technology, Wiejska 45C, Bialystok, Poland.
Arkadiusz MystkowskiDepartment of Automatic Control and Robotics, Bialystok University of Technology, Wiejska 45D, Bialystok, 15-351, Poland.

Funding

Ministry of Science and Higher Education (Poland) 7135/IA/SP/2020Ministry of Science and Higher Education (Poland) MRID/WM/5/2024
6 · The paper itself

Abstract

PDMS/NdFeB composites are promising materials for soft magnetic actuators, but NdFeB particles corrode in body fluids and release toxic metal ions, limiting their biomedical use. We developed ~ 100 µm spin-coated PDMS-chitosan (PDMS-CHIT) and PDMS-polycaprolactone (PDMS-PCL) coatings that solve this problem. Over 24 weeks of immersion, these coatings reduced neodymium and iron release by more than 95%, keeping ion concentrations well below cytotoxicity thresholds. Importantly, the PDMS-PCL coating fully preserved magnetorheological actuation (ΔG' ≈ 61 kPa under 0.5 T, comparable to uncoated composite), while PDMS-CHIT provided superior ion barrier at the cost of reduced actuation force. Biological validation confirmed cytocompatibility with fibroblasts, hemocompatibility with erythrocytes, and strong suppression of bacterial biofilm formation. These results establish a validated materials platform for biocompatible soft magnetic actuators.

Indexed as

ChitosanCoated Materials, BiocompatibleDimethylpolysiloxanesElastomersPolyestersAnimalsBiofilmsFibroblastsHumansIronMaterials TestingNeodymiumbaysilonChitosanCoated Materials, BiocompatibleDimethylpolysiloxanesElastomersIronNeodymiumpolycaprolactonePolyestersChitosanCytocompatibilityFlexible materialHemocompatibilityMagnetic compositesMagnetorheologyPolycaprolactone

Identifiers

PMID41680289
PMCPMC12976346

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.