Evidence map›Paper›PMID 41680396›Full record

ArticleNPJ precision oncology2026

OnCorr: A pan-cancer mRNA-protein correlation tool for precision oncology.

Urwah Nawaz, Niantao Deng, Ori Livson, Chelsea Mayoh, Loretta M S Lau, Roger R Reddel, Bhavna Padhye, Rebecca C Poulos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Urwah NawazProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.
Niantao DengProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.
Ori LivsonProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.
Chelsea MayohChildren's Cancer Institute at Minderoo, Children's Comprehensive Cancer Centre, Sydney, NSW, Australia.
Loretta M S LauChildren's Cancer Institute at Minderoo, Children's Comprehensive Cancer Centre, Sydney, NSW, Australia.
Roger R ReddelProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.
Bhavna PadhyeCancer Centre for Children, The Children's Hospital at Westmead, Westmead, NSW, Australia.
Rebecca C PoulosProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. rpoulos@cmri.org.au.

Funding

Cancer Council NSW IG 18-01Cancer Institute New South Wales (NSW) 2017/TPG001, REG171150CINSW Program Grant 2021/TPG2112Medical Research Future Fund MRFF-PDNational Breast Cancer Foundation IIRS-18-164National Health and Medical Research Council (NHMRC) of Australia European Union grant (GNT1170739, a companion grant to support the 'iPC-individualized Paediatric Cure' [ref. 826121])National Health and Medical Research Council (NHMRC) of Australia GNT2000855, GNT1138536NHMRC Synergy Grant APP2018642NSW Ministry of Health CMP-01Sydney Cancer Partners Translational Partners Fellowship 2021/CBG0002
6 · The paper itself

Abstract

Proteins are ultimately responsible for cellular phenotypes and are targeted by most anticancer drugs. However, beyond immunohistochemistry, proteins are not typically measured in precision oncology, meaning transcriptomics is used as a proxy. To determine how informative mRNA is for guiding personalised treatments, mRNA-protein correlations were analysed in three large pan-cancer datasets and made available in a web portal ( https://oncorr.aws.procan.org.au/ ). OnCorr can be integrated into precision medicine programs to augment transcriptomics.

Identifiers

PMID41680396
PMCPMC13009198

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.