ArticleCommunications biology2026
Heterogeneity between VIP and GRP neurons underlies AVP receptor signaling in the mouse suprachiasmatic nucleus.
Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Intracrine androgen metabolism in the meibomian gland: regulation, circadian control, and implications in dry eye disease.Endocrine journal · 2026Review
- Corticotropin-releasing factor as a regulator of adrenal glucocorticoid synthesis and brain function: a scientific journey of a neuroendocrine physician.Endocrine journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Understanding the network topology of a cluster of diverse neurons acting in concert requires a detailed expression map of ligand-receptor pairs involved in cell-cell communication. The neuropeptide arginine vasopressin (AVP) and signaling mediated by its cognate receptor V1a have been implicated in dorsal-to-ventral regional communication in the suprachiasmatic nucleus (SCN), a cluster of neurons that acts in concert to generate daily rhythms in behavior and physiology. Here, we show that among vasoactive intestinal peptide (VIP)-ergic neurons in the ventral SCN only a small subpopulation expresses V1a, and we demonstrate the requirement of V1a in these VIP neurons for maintaining the robustness of the circadian clock using a jet-lag paradigm. Notably, we found that V1a expression appears to be minimal in the other major ventral neuronal population expressing gastrin-releasing peptide (GRP). The identified heterogeneity between VIP and GRP neurons, and among VIP neurons, provides a basic map for understanding the cryptic network structure from dorsal AVP neurons to receiver ventral SCN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.