Evidence map›Paper›PMID 41680892›Full record

Trial reportTrials2026

A study on the effect of blood flow restriction training on the recovery of lower limb motor function in stroke patients with hemiplegia: a randomized controlled trial.

Zhang Qin, Luo Binyu, Wen Qian, Wang Li, Jia Jiameng, Lin Xia

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Zhang QinRehabilitation Medicine Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637008, China.
Luo BinyuDepartment of Gastrointestinal Hernia Surgery, The Second Clinical Medical College of North Sichuan Medical College, Nanchong Central Hospital (Beijing Anzhen Nanchong Hospital), Nanchong, Sichuan, 63700, China.
Wen QianRehabilitation Medicine Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637008, China.
Wang LiRehabilitation Medicine Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637008, China.
Jia JiamengRehabilitation Medicine Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637008, China.
Lin XiaRehabilitation Medicine Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637008, China. linxiaqiu01@163.com.

Funding

Development Plan Project of Affiliated Hospital of North Sichuan Medical College 2020JC023
6 · The paper itself

Abstract

backgroundTo investigate the effect of blood flow restriction training (BFRT) on lower limb motor function recovery in stroke patients with hemiplegia.

methodsIn this parallel-group, assessor-blinded, randomized controlled trial, 80 patients with first-ever stroke (ischemic or hemorrhagic) were enrolled. Participants were randomly allocated to receive either routine rehabilitation (RR group, n = 40) or routine rehabilitation plus BFRT (RR + BFRT group, n = 40) for 8 weeks (5 days/week). Assessments performed before and after the intervention included the Fugl-Meyer Assessment of the Lower Extremity (FMA-LE), Berg Balance Scale (BBS), Modified Barthel Index (MBI), 6-Minute Walk Test (6MWT), and Manual Muscle Testing (MMT) for key lower limb muscles.

resultsBaseline characteristics and all outcome measures were comparable between the two groups (all P > 0.05). After the intervention, both groups showed significant within-group improvements in FMA-LE, BBS, MBI, 6MWT, and MMT scores (all P < 0.05). The RR + BFRT group demonstrated significantly greater improvement than the RR group in FMA-LE, BBS, MBI, 6MWT, and MMT scores for the iliopsoas, quadriceps, and hamstrings (all P < 0.05). No between-group difference was found for tibialis anterior muscle strength (P > 0.05).

conclusionsAdjunctive BFRT can effectively enhance lower limb motor function, balance, walking capacity, and muscle strength in stroke patients with hemiplegia, leading to greater functional independence. BFRT appears to be a beneficial adjunct to routine stroke rehabilitation.

Indexed as

Blood Flow Restriction TherapyHemiplegiaIschemic StrokeLower ExtremityMotor ActivityMuscle, SkeletalStrokeStroke RehabilitationAgedFemaleFunctional StatusHumansMaleMiddle AgedRecovery of FunctionRegional Blood FlowBlood flow restriction training (BFRT)HemiplegiaRehabilitation therapyStroke

Identifiers

PMID41680892
PMCPMC13005518

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.