Evidence map›Paper›PMID 41681490›Full record

ArticleAnimals : an open access journal from MDPI2026

Genomic Signatures Underlying Environmental Adaptation and Reproductive Traits in the Tibetan Pig.

Mengqi Duan, Songyuan Zhang, Hang Jiao, Peng Shang, Chunli Li, Kejun Wang

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Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mengqi DuanCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Songyuan ZhangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Hang JiaoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0009-0007-7923-6049
Peng ShangCollege of Animal Science, Xizang Agriculture and Animal Husbandry University, Linzhi 860000, China.
Chunli LiCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0002-9071-161X
Kejun WangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0003-4337-980X

Funding

Biological Breeding-Major Projects in National Science and Technology 2023ZD0404404Program for Innovative Research Talents inUniversity of Henan Province 25HASTIT043Science and Technology Program Project of Tibet Autonomous Region XZ202501ZY0147Zhongyuan Young Top Talents forScientific and Technological Innovation Project. NO
6 · The paper itself

Abstract

backgroundThe Tibetan pig, a highland breed with exceptional adaptability to harsh environments (cold, hypoxia, coarse feed) but poor growth/reproductive traits, was studied to uncover genetic mechanisms and support breeding improvements.

methodsWe conducted de novo genome assembly of a male Tibetan pig using stLFR sequencing, supplemented with ONT data, and compared the assembly to the Duroc pig genome (v11.1).

resultsThe assembled genome (2.25 Gb, contig N50 = 136.5 Mb, GC content = 41.74%, 94.16× coverage) showed 96.9% BUSCO completeness. Structural variant (SV) analysis identified 22,008 insertions and 27,639 deletions, with an SV genotyping accuracy of 0.9735. Selective sweep analysis highlighted adaptive genes:

conclusionsThis study provides a chromosome-level genome assembly of a male Tibetan pig (generated from stLFR and ONT data), and, through whole-genome resequencing of 124 Tibetan sows, identifies key genetic factors underlying Tibetan pigs' environmental adaptability and reproductive limitations, enabling genomic strategies to enhance breeding efficiency while preserving adaptive traits.

Indexed as

genome assemblystructural variationTibetan pigwhole-genome resequencing

Identifiers

PMID41681490
PMCPMC12896720

What Socratic holds

Textmetadata
LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.