Evidence map›Paper›PMID 41683013›Full record

ReviewFoods (Basel, Switzerland)2026

Advances in Proteomics and Functional Foods from Fermentation and Bioencapsulation of Andean Grains and Tubers: Applications and Perspectives.

Wendy Akemmy Castañeda-Rodríguez, Abel José Rodríguez-Yparraguirre, Carlos Diego Rodríguez-Yparraguirre, Wilson Arcenio Maco-Vásquez, Iván Martín Olivares-Espino, Andrés D Epifanía-Huerta, Oswaldo Lara-Rivera, Elías Guarniz-Vásquez, César Moreno-Rojo, Elza Aguirre

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wendy Akemmy Castañeda-RodríguezDoctoral Program in Agro-Industrial Engineering, Specialization in Advanced Processing of Andean Grains and Tubers, Universidad Nacional del Santa, Nuevo Chimbote 02712, Ancash, Peru.ORCID 0000-0002-5670-861X
Abel José Rodríguez-YparraguirreDepartment of Agroindustry and Agronomy, Faculty of Engineering, Universidad Nacional del Santa, Nuevo Chimbote 02712, Ancash, Peru.ORCID 0000-0002-2434-4663
Carlos Diego Rodríguez-YparraguirreGraduate School, Universidad Nacional de Trujillo, Trujillo 130101, La Libertad, Peru.ORCID 0000-0001-8527-8148
Wilson Arcenio Maco-VásquezGraduate School, Universidad Nacional de Trujillo, Trujillo 130101, La Libertad, Peru.ORCID 0000-0002-0557-819X
Iván Martín Olivares-EspinoGraduate School, Universidad Nacional de Trujillo, Trujillo 130101, La Libertad, Peru.
Andrés D Epifanía-HuertaGraduate School, Universidad Privada de Trujillo, Trujillo 130101, La Libertad, Peru.
Oswaldo Lara-RiveraGraduate School, Universidad Nacional de Barranca, Barranca 15312, Lima, Peru.
Elías Guarniz-VásquezGraduate School, Universidad Privada San Pedro, Chimbote 02803, Ancash, Peru.
César Moreno-RojoDepartment of Agroindustry and Agronomy, Faculty of Engineering, Universidad Nacional del Santa, Nuevo Chimbote 02712, Ancash, Peru.ORCID 0000-0002-7143-4450
Elza AguirreDepartment of Agroindustry and Agronomy, Faculty of Engineering, Universidad Nacional del Santa, Nuevo Chimbote 02712, Ancash, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transformation of Andean grains and tubers through fermentation and bioencapsulation has emerged as a key strategy to enhance their nutritional, functional, and biotechnological value, driven by advances in proteomic and metabolomic techniques. This study aimed to systematize recent evidence on the biochemical and functional modifications induced by these processes and their potential application in the development of functional foods. The methodology integrated 67 studies analyzed using tools such as R 4.5.1 with the JupyterLab interface 4.5.2, SCImago Graphica Beta 1.0.53, and VOSviewer 1.6.20, incorporating data generated through LC-MS/MS, UHPLC-QTOF, Orbitrap platforms, transcriptomics, and combined omics approaches, considering original studies published between 2020 and 2025. The main findings indicate substantial increases in free amino acids (up to 64.8%), phenolic compounds (2.9-5.2%), and antioxidant activity (up to 45%), along with the identification of 430 polyphenols, 90 flavonoids, 14 novel oxindole acetates, and bioactive peptides with IC50 values ranging from 0.51 to 0.78 mg/mL. Bioencapsulation showed controlled release of bioactive compounds, highlighting nanocapsules of 133-165 nm with a maximum release of 9.86 mg GAE/g. In conclusion, the combination of fermentation and encapsulation enhances the stability, bioavailability, and functionality of Andean crops, supporting their industrial adoption for the development of sustainable nutraceutical foods that improve health and promote the valorization of traditional resources.

Indexed as

biotechnologybiotransformationfunctional foodspeptidespseudocerealssustainability

Identifiers

PMID41683013
PMCPMC12897397

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.