Evidence map›Paper›PMID 41683744›Full record

ArticleInternational journal of molecular sciences2026

Neuroprotective Potential of

Patrycja Kupnicka, Izabela Szućko-Kociuba, Alicja Trzeciak-Ryczek, Michalina Ptak, Katarzyna Piotrowska, Maciej Kołodziejczak, Irena Baranowska-Bosiacka

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrycja KupnickaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0002-0756-6483
Izabela Szućko-KociubaInstitute of Biology, University of Szczecin, 13 Wąska, 71-415 Szczecin, Poland.ORCID 0000-0002-2974-1908
Alicja Trzeciak-RyczekInstitute of Biology, University of Szczecin, 13 Wąska, 71-415 Szczecin, Poland.ORCID 0000-0003-4740-9471
Michalina PtakDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, 70-111 Szczecin, Poland.
Katarzyna PiotrowskaDepartment of Physiology, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0002-4472-0830
Maciej KołodziejczakDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0009-0007-5551-1659
Irena Baranowska-BosiackaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0001-9187-8895

Funding

Pomeranian Medical University WM-130/S/2025
6 · The paper itself

Abstract

Exposure to lead is associated with microglial dysfunction and the development of neuroinflammation. This contributes to accelerated neurodegeneration. Even low doses of this element modulate inflammatory responses and might contribute to central nervous system dysfunction. Extracts from the mushroom

Indexed as

HericiumInflammationLeadMacrophagesNeuroprotective AgentsSignal TransductionChemokine CCL2Cyclooxygenase 2DinoprostoneHumansMicrogliaTHP-1 CellsTumor Necrosis Factor-alphaChemokine CCL2Cyclooxygenase 2DinoprostoneLeadNeuroprotective AgentsTumor Necrosis Factor-alphaHericium erinaceusimmunomodulationinflammationmacrophageneurodegenerationneuroprotection

Identifiers

PMID41683744
PMCPMC12898474

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.