Evidence map›Paper›PMID 41683751›Full record

ArticleInternational journal of molecular sciences2026

A Proteomic Study of the Dual Oncogenic and Tumor-Suppressive Roles of SIRT3 in Lung and Breast Cancer Cell Lines.

Marisol Ayala Reyes, Diana Lashidua Fernández Coto, Ramiro Alonso Bastida, György Marko-Varga, Jeovanis Gil, Sergio Encarnación-Guevara

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marisol Ayala ReyesCentro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62230, Morelos, Mexico.ORCID 0009-0003-3486-0949
Diana Lashidua Fernández CotoCentro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62230, Morelos, Mexico.
Ramiro Alonso BastidaCentro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62230, Morelos, Mexico.ORCID 0009-0007-1449-1145
György Marko-VargaClinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, 22242 Lund, Sweden.
Jeovanis GilClinical Chemistry Section, Department of Translational Medicine, Lund University, 22242 Lund, Sweden.ORCID 0000-0003-3601-3893
Sergio Encarnación-GuevaraCentro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62230, Morelos, Mexico.ORCID 0000-0001-7889-1681

Funding

Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica (PAPIIT-UNAM) IN-213522 and IN216626
6 · The paper itself

Abstract

Mitochondria play a crucial role in metabolism and energy production by generating adenosine triphosphate (ATP) through oxidative phosphorylation. They also help maintain intracellular calcium levels, facilitate communication between the nucleus and cytoplasm, detoxify reactive oxygen species (ROS), and regulate apoptosis. Reversible acetylation of mitochondrial proteins is a key post-translational modification influencing these processes, with the NAD

Indexed as

Breast NeoplasmsLung NeoplasmsProteomeProteomicsSirtuin 3A549 CellsAcetylationCell Line, TumorFemaleHumansMCF-7 CellsMetabolic ReprogrammingMitochondriaMitochondrial ProteinsProtein Processing, Post-TranslationalMitochondrial ProteinsProteomeSIRT3 protein, humanSirtuin 3acetylationcancermetabolismmitochondriaoxidative phosphorylationpost-translational modificationsirtuin

Identifiers

PMID41683751
PMCPMC12898715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.