Evidence map›Paper›PMID 41683816›Full record

ReviewInternational journal of molecular sciences2026

Molecular Biomarkers in IgE Immunoassays Used for Grass Pollen Allergy Diagnosis in European Clinical Settings.

Lorena-Mihaela Gheorghita, Mariana Preda, Carmen-Saviana Marghidan, Miruna-Ioana Lazar, Ioana-Raluca Papacocea, Sylwia Smolinska, Florin-Dan Popescu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorena-Mihaela GheorghitaDepartment of Physiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mariana PredaDepartment of Allergology Nicolae Malaxa Clinical Hospital, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 022441 Bucharest, Romania.ORCID 0000-0001-7396-5688
Carmen-Saviana MarghidanAllergology and Clinical Immunology Department, Nicolae Malaxa Clinical Hospital, 022441 Bucharest, Romania.
Miruna-Ioana LazarAllergology and Clinical Immunology Department, Nicolae Malaxa Clinical Hospital, 022441 Bucharest, Romania.
Ioana-Raluca PapacoceaDepartment of Physiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Sylwia SmolinskaDepartment of Clinical Immunology, Faculty of Medicine, Wroclaw Medical University, 51-616 Wroclaw, Poland.ORCID 0000-0001-6736-2696
Florin-Dan PopescuDepartment of Allergology Nicolae Malaxa Clinical Hospital, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 022441 Bucharest, Romania.ORCID 0000-0001-6316-3155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grass pollen allergy has a high prevalence worldwide, making an accurate diagnosis critical in the framework of multifaceted environmental exposures. Our narrative review provides a comprehensive synopsis of component-resolved diagnosis biomarkers for pollen of Pooideae and Chloridoideae grasses, along with practical approaches in European clinical settings. We present a structured overview of allergen components utilized in singleplex, multiparameter, and multiplex IgE immunoassays. Molecular biomarkers have key roles in distinguishing genuine grass pollen sensitization from cross-reactivity and in assessing the risks associated with various IgE sensitization patterns, thereby enabling precise allergy diagnosis and facilitating targeted allergen immunotherapy. Diagnostic algorithms are provided to assist clinicians in making molecular biomarker-based personalized decisions. This tailored approach supports better management of patients with grass pollen sensitizations and allergies.

Indexed as

AllergensBiomarkersImmunoglobulin EPoaceaePollenRhinitis, Allergic, SeasonalCross ReactionsEuropeHumansImmunoassayAllergensBiomarkersImmunoglobulin Ebiomarkersgrass pollen allergymolecular diagnosis

Identifiers

PMID41683816
PMCPMC12898073

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.