Evidence map›Paper›PMID 41683849›Full record

ReviewInternational journal of molecular sciences2026

The Role of Vitamins and Micronutrients in the Prevention of Melanoma: A Review of Current Evidence.

Joanna Pec, Weronika Pająk, Jakub Kleinrok, Kamil Rusztyn, Jolanta Flieger, Barbara Teresińska, Alicja Forma, Jacek Baj

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanna PecChair and Department of Forensic Medicine, Medical University of Lublin, Ul. Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0009-0000-5525-7338
Weronika PająkChair and Department of Forensic Medicine, Medical University of Lublin, Ul. Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0009-0009-9616-0458
Jakub KleinrokChair and Department of Forensic Medicine, Medical University of Lublin, Ul. Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0009-0006-3742-5696
Kamil RusztynFaculty of Medicine, Medical University of Warsaw, Ul. Żwirki i Wigury 61, 02-091 Warsaw, Poland.ORCID 0009-0000-9764-3907
Jolanta FliegerDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a (Collegium Pharmaceuticum), 20-093 Lublin, Poland.ORCID 0000-0001-6881-3161
Barbara TeresińskaDoctoral School, Medical University of Lublin, Chodźki 7, 20-093 Lublin, Poland.ORCID 0000-0002-1101-3566
Alicja FormaChair and Department of Forensic Medicine, Medical University of Lublin, Ul. Jaczewskiego 8b, 20-090 Lublin, Poland.
Jacek BajDepartment of Correct, Clinical, and Imaging Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0002-1372-8987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is a type of skin cancer with an increasing incidence rate worldwide and a high mortality rate. In addition to known risk factors, such as UV exposure and genetic predisposition, researchers are paying more attention to the role of diet, micronutrients, and vitamins in preventing melanoma. This review discusses the effects of selected vitamins (D, A, C, and E), trace elements, and bioactive compounds (polyphenols and omega-3 fatty acids) on biological processes related to melanoma development. The review considered both antioxidant and immunomodulatory effects, as well as effects on DNA repair and photoprotection. The significance of polymorphisms of genes encoding receptors and enzymes that metabolize the compounds studied was also analyzed. The results suggest that maintaining adequate levels of these substances may promote melanoma prevention, particularly among individuals at risk. However, caution in the use of supplementation is necessary due to the possible biphasic effects of some micronutrients. Further clinical trials are needed to develop effective, safe prevention strategies based on micronutrients and vitamins.

Indexed as

MelanomaMicronutrientsSkin NeoplasmsVitaminsAnimalsAntioxidantsDietary SupplementsHumansAntioxidantsMicronutrientsVitaminsmelanomamicronutrientsnutritionoxidative stresspreventionvitamins

Identifiers

PMID41683849
PMCPMC12898263

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.