Evidence map›Paper›PMID 41684800›Full record

Trial reportFrontiers in psychiatry2026

Clinical efficacy observation of repetitive transcranial magnetic stimulation combined with auditory integration training in children with ASD.

Qing-Hong Hao, Jin-Ying Wang, Jin-di Yang, Yao Tong, Lei Xiao, Xiao-Qin Zeng, Wei Li, Su-Fen Hu, Zhi-Hai Lv

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qing-Hong Hao *Department of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Jin-Ying Wang *Department of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Jin-di Yang *Department of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Yao TongDepartment of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Lei XiaoDepartment of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Xiao-Qin ZengDepartment of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Wei LiDepartment of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Su-Fen HuDepartment of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Zhi-Hai LvDepartment of Child Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autism spectrum disorder (ASD) has become a major public health issue of global concern and has attracted the attention of researchers in recent years. Due to the high incidence and persistent lifelong dysfunction of children with ASD, exploring active and effective intervention strategies plays a key role in their prognosis. Repetitive transcranial magnetic stimulation (rTMS) and auditory integration training (AIT) are both promising neuromodulation methods and play an important role in clinical intervention in children with ASD. This study aims to explore the clinical effectiveness of rTMS and AIT combined intervention compared with single intervention through randomized controlled experiments, and provide scientific basis for clinical intervention in ASD. Methods: A total of 60 participants with ASD were randomly assigned to the study group (rTMS combined with AIT) and the control group (rTMS) in a 1:1 ratio, with 30 participants in each group. The outcome indicators were the Autism Behavior Checklist (ABC), the Childhood Autism Rating Scale (CARS), the Strengths and Difficulties Questionnaire (SDQ), and the Repetitive Behavior Scale-Revised (RBS-R). Clinical data were collected at baseline and after intervention. Data were processed and analyzed by SPSS. Results: After 12 weeks of intervention, the total scores of ABC, CARS, SDQ and RBS-R in the two groups were significantly improved compared with those before intervention ( Discussion: The intervention therapy of rTMS combined with AIT has significant efficacy in children with ASD, which can significantly improve the core symptoms and emotional behavioral problems of children with ASD. This method is worthy of being promoted and applied in clinical practice. Clinical trial registration: https://www.chictr.org.cn/showproj.html?proj=225665, identifier ChiCTR2400082706.

Indexed as

auditory integration trainingautism spectrum disordercombined interventionrandomized controlled trialrepetitive transcranial magnetic stimulation

Identifiers

PMID41684800
PMCPMC12891170

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.