ArticleOrganic letters2026
Electrochemical Activation of Bicyclo[1.1.0]butanes.
Article in Organic letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- Pulsed electrolysis enables unexpected lactonization of bicyclobutane carboxylic acids.Chemical science · 2026Article
- Electrochemical synthesis of 2-oxa-bicyclo[2.1.1]hexanes by anodic oxidation-cyclization relay strategy.Chemical science · 2026Article
- Electrochemically driven strain-release dearomative (3 + 2) cyclization for the synthesis of bicyclo[2.1.1]hexane-fused polycyclic spiroindolines.Chemical science · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herein, we describe a novel, light, and catalyst-free electrochemical method for the activation of bicyclo[1.1.0]butanes (BCBs) enabling cycloaddition with aldehydes and arylation with arenes. This exceptionally mild strategy for BCB functionalization leverages preliminary anodic oxidation in concert with strain release to facilitate the formation of oxabicyclohexanes (oBCHs) and bis-arylated cyclobutane products. A plausible electrolytic mechanism is proposed, alongside insights garnered from mechanistic studies.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.