Evidence mapPaperPMID 41685607Full record

ArticleOncology reports2026

Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma.

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao

Abstract read
In one paragraph

Article in Oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengnan GuoDepartment of Respiratory Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050051, P.R. China.
He LiDepartment of Respiratory Medicine, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei 441021, P.R. China.
Zhifang ZhaoDepartment of Respiratory Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Yuanyuan WangDepartment of Respiratory Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Jiaqi TangDepartment of Respiratory Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Binghan ZhongDepartment of Respiratory Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Yunxia ZhaoDepartment of Respiratory Medicine, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050051, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The poor prognosis and high mortality rate of non‑small cell lung cancer are largely driven by its aggressive migratory and invasive behavior. Epithelial‑mesenchymal transition (EMT) is a central mechanism conferring these malignant traits. The present study examined the expression profile of the sodium channel β4 subunit (

Indexed as

Adenocarcinoma of LungEpithelial-Mesenchymal TransitionLung NeoplasmsVoltage-Gated Sodium Channel beta-4 SubunitA549 CellsAgedApoptosisBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedBiomarkers, TumorSCN4B protein, humanVoltage-Gated Sodium Channel beta-4 Subunitepithelial‑mesenchymal transitioninvasionlung adenocarcinomamigrationsodium channel β4 subunitThe Cancer Genome Atlas

Identifiers

PMID41685607
PMCPMC12917569

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.