Evidence map›Paper›PMID 41685698›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2026

Enantiopurity-Dependent Peptide Coacervates and Asymmetric Organocatalysis.

Alice Vetrano, Nico di Fonte, Olivier Monasson, Federico Perrella, Martina Porco, Ferdinando Mercuri, Gianluca Dell'Orletta, Francesco Petragnano, Alessio Carioscia, Davide Deodato and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Alice VetranoDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Nico di FonteDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Olivier MonassonCNRS, BioCIS, C.Y. Cergy Paris Université, Cergy Pontoise, France.
Federico PerrellaDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Martina PorcoDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Ferdinando MercuriDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Gianluca Dell'OrlettaDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Francesco PetragnanoDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Alessio CariosciaDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Davide DeodatoDepartment of Chemical Sciences, University of Catania, Catania, Italy.
Damiano CalcagnoIRCCS-Fondazione Bietti, Rome, Italy.
Giovanna SalvittiDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Samantha RealeDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Fabio PesciaioliDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Carino FerranteCNR- SPIN, C/O Department of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Davide TedeschiDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Giuseppe GrassoDepartment of Chemical Sciences, University of Catania, Catania, Italy.
Paola BenassiDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.
Elisa PeroniCNRS, BioCIS, C.Y. Cergy Paris Université, Cergy Pontoise, France.
Armando CarloneDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0003-2983-6445
Isabella DaidoneDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0001-8970-8408
Claudio IacobucciDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0001-9592-3606

Funding

European Union Next Generation EU P20224WAMEEuropean Union Next Generation EU P2022YM7F2European Union Next Generation EU PRIN 2022 PNRREuropean Union-NextGenerationEUFresenius Kabi iPSUMItalian Ministry of University and Research 20225HNCZKItalian Ministry of University and Research (MUR) National Innovation Ecosystem CUP E13C22001060006Italian Ministry of University and Research (MUR) National Innovation Ecosystem ECS00000041
6 · The paper itself

Abstract

Membraneless compartmentalization via liquid-liquid phase separation (LLPS) has emerged as a powerful strategy to organize biochemical reactions. Recently, peptide-based coacervates demonstrated the potential to function as microreactors by enhancing reaction kinetics through increased local concentrations and altered microenvironments. Here, we introduce an O-methylated diphenylalanine-based tripeptide

Indexed as

PeptidesCatalysisMolecular Dynamics SimulationPhase SeparationStereoisomerismPeptideschiralitycoacervatesliquid‐liquid phase separationLLPSsupramolecular chemistry

Identifiers

PMID41685698
PMCPMC13054208

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.