Evidence mapPaperPMID 41686271Full record

ArticleMolecular genetics and genomics : MGG2026

Genome-wide association study reveals acute mountain sickness susceptibility in Chinese population.

Xiangyi Zheng, Wenyu Song, Yuanfeng Li, Nandi Bao, Wenhui Li, Yang Liu, Juanjuan Liu, Bin Li, Xi Yang, Xiaobo Han and 9 more

Abstract read
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In one paragraph

Article in Molecular genetics and genomics : MGG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xiangyi Zheng *Laboratory of Clinical Medicine, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Wenyu Song *State Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China.
Yuanfeng LiState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China.
Nandi Bao *Senior Department of Cardiology, the Sixth Medical Center of PLA General Hospital, Beijing, 100048, China.
Wenhui Li *Department of Clinical Laboratory Medicine, The Fifth People's Hospital of Qinghai Province, Xining, 810001, China.
Yang Liu *Second Outpatient Department Diagnostic and Treatment Clinic, The 964th Hospital of the Chinese People's Liberation Army Joint Logistics Support Force, Changchun, 130000, China.
Juanjuan LiuDepartment of Geriatrics, First People's Hospital of Qujing, Qujing, 655000, China.
Bin LiGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Xi YangGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Xiaobo HanGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Jialin WuGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Liqun MaGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Ying LiuGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Mei JinGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Guangyun WangLaboratory of Clinical Medicine, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Dongfeng YinGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China.
Wei ZhouDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, 27 Taiping Road, Beijing, 100850, China. zhouweisyl802@163.com.
Qiao YeLaboratory of Clinical Medicine, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China. yeqiao333@163.com.
Rui WangGeneral Hospital of Xinjiang Military Command, PLA. 359 Youhao North Road, Urumqi, 830000, China. urumqi@126.com.ORCID http://orcid.org/0000-0001-8140-2914

Funding

Science and Technology Department of Xinjiang Uygur Autonomous Region No.2022B03005
6 · The paper itself

Abstract

Acute mountain sickness (AMS) is a major health challenge in high-altitude environments, yet its genetic underpinnings, particularly in the Chinese population, remain poorly characterized. We conducted a genome-wide association study (GWAS) on 156 AMS patients and 313 controls in Chinese population, revealing four novel suggestive single nucleotide polymorphisms (SNPs) (P < 1 × 10

Indexed as

Altitude SicknessGenetic Predisposition to DiseaseGenome-Wide Association StudyAcute DiseaseAdultAllelesCase-Control StudiesChinaEast Asian PeopleFemaleHumansMalePolymorphism, Single NucleotideUbiquitin-Protein LigasesUbiquitin-Protein LigasesAMSBPGMGWASUHRF2

Identifiers

PMID41686271

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.