ArticleBMC plant biology2026
Brachypodium HISTONE DEACETYLASE 19.1 promotes yield, flowering, and freezing tolerance at the expense of drought tolerance.
Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundAntagonistic pleiotropy can lead to tradeoffs whereby changes at a single locus positively and negatively affect two fitness traits, respectively. In plants, hormone signaling genes are good candidates for such pleiotropy, as they often work at the expense of alternative hormone pathways. In Arabidopsis thaliana, HISTONE DEACETYLASE 19 (HDA19) stimulates growth at the expense of drought tolerance by repressing the brassinosteroid (BR) pathway.
resultsTo determine if orthologous genes in grasses function in a similar manner, we characterized one of two HDAC19 genes in the temperate model grass Brachypodium distachyon. Partially supporting a molecular tradeoff in growth and reproduction versus drought tolerance, hdac19.1 mutants were late flowering and shorter with smaller/lighter seed under control conditions and proportionally larger with higher survival under drought conditions. Mutants also showed reduced growth sensitivity to brassinolide treatment. Evidence of weaker antagonistic pleiotropy was found between drought and freezing tolerance, in line with previous studies showing a tradeoff between these stressors in Pooideae grasses.
conclusionsBy modulating brassinosteroid responsiveness, HDAC19.1 appears to act as a molecular lever governing the tradeoff between growth, reproductive output and freezing tolerance versus drought tolerance.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.