ArticleEJNMMI physics2026
Patlak-PBNT: a simple population-based Patlak model to generate [
Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
purposeThe objective of this study is to generate reliable K
methodsWe proposed a population-based Patlak model named Patlak-PBNT, which incorporates a population-based "normalized time" (PBNT) into the traditional Patlak plot. This model does not require long-duration PET scans to obtain an image-derived input function (IDIF) of full measured kinetics, thereby generating reliable K
resultsCompared to the traditional Patlak, Patlak-PBNT effectively reduces PET scan duration while maintaining the quality of generated K
conclusionThe proposed Patlak-PBNT model reduces the dependency on a complete input function, thereby avoiding the need for long-duration PET scans typically required to obtain a full input function. When utilizing dynamic PET images of identical scan durations (20-60 min post-injection), the K
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