Evidence map›Paper›PMID 41690338›Full record

ArticleNeuroImage2026

Alteration of water exchange rates following focused ultrasound-mediated BBB opening in the dorsal striatum of non-human primates: A diffusion-prepared pCASL study.

Dong Liu, Xingfeng Shao, Fabian Munoz Silva, Soroosh Sanatkhani, Ray Lee, Elisa E Konofagou, Danny Jj Wang, Vincent P Ferrera

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Dong LiuDept. of Neuroscience, Columbia University, New York, NY, USA; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA. Electronic address: dl3341@columbia.edu.
Xingfeng ShaoStevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Fabian Munoz SilvaDept. of Neuroscience, Columbia University, New York, NY, USA; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Soroosh SanatkhaniDept. of Neuroscience, Columbia University, New York, NY, USA; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Ray LeeDept. of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Elisa E KonofagouDept. of Biomedical Engineering, Columbia University, New York, NY, USA; Dept. of Radiology, Columbia University, New York, NY, USA.
Danny Jj WangStevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Vincent P FerreraDept. of Neuroscience, Columbia University, New York, NY, USA; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA; Dept. of Psychiatry, Columbia University, New York, NY, USA.

Funding

Focused ultrasound for memory disordersR01MH133020 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VINCENT P FERRERA, Elisa E. Konofagou · 2023 to 2026
$3.1M
Non-invasive MRI mapping of BBB water exchange rate and permeabilityR01NS134712 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Danny JJ WANG · 2024 to 2026
$2.1M
NIMH NIH HHS R01 MH133020NINDS NIH HHS R01 NS134712
6 · The paper itself

Abstract

This study applied diffusion-prepared pseudo-continuous arterial spin labeling (DP-pCASL) to quantify cerebral blood flow (CBF), arterial transit time (ATT), and blood-brain barrier (BBB) water exchange rate (K

Indexed as

Blood-Brain BarrierBody WaterCerebrovascular CirculationCorpus StriatumWaterAnimalsDiffusion Magnetic Resonance ImagingMacaca mulattaMaleMicrobubblesSonicationSpin LabelsSpin LabelsWaterBlood-brain barrier opening (BBBO)Contrast-free biomarkerDiffusion-prepared pseudo-continuous arterial spin labeling (DP-pCASL)Focused ultrasound (FUS)Water exchange rates

Identifiers

PMID41690338
PMCPMC13016081

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.