ArticleSmall (Weinheim an der Bergstrasse, Germany)2026
"Tone-Arm" Neuromodulation MEMS Microcoil for In Vivo Imaging.
Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Implantable neural interfaces have revolutionized neuromodulation by enabling bidirectional communication between neural circuits and external devices. Yet, existing modalities face important challenges in precision, high invasiveness, and compatibility with advanced in vivo imaging systems. We report a MEMS-based "tone-arm" micro-coil design optimized for vertical cortical insertion, featuring an 800-µm cantilever with a small cross-section that reconciles mechanical robustness with two-photon microscopy compatible miniaturization. Numerical modeling spanning electromagnetic field gradients, thermodynamic safety margins, and buckling resistance guided our MEMS device design process. Our toxic-etchants-free 3-stage and 4-mask fabrication process yielded micro-coil devices compatible with in vivo two-photon imaging. Our vertically integrated probe design overcomes longstanding optical obstruction challenges, preserving >95% imaging field visibility during in vivo studies. This platform enables simultaneous micromagnetic neuromodulation and subcellular-resolution calcium imaging, opening unprecedented opportunities to dissect neural circuit dynamics during targeted intervention. Thermodynamic modelling showed the record low probe resistance (2 Ω) is safe for implantation and limits tissue heating to < 0.2°C. The low-invasive cross-section (70 × 86 µm
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.