ArticleStem cell research & therapy2026
Ningxue Shengban decoction containing serum alleviates immune thrombocytopenia by modulating CD4
Article in Stem cell research & therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe abnormal immune response mediated by CD4
aimThis study aims to clarify the role of exosomal miR-199a-5p derived from bone marrow mesenchymal stem cells (BMSCs) in immune homeostasis, and to explore the therapeutic effects of exosomes from BMSCs(BMSCs-Exo) pretreated with NXSBD containing serum on ITP.
methodWe co-cultured CD4
resultsOur results indicate that the immunomodulatory effect of BMSCs-Exo on CD4
conclusionIn conclusion, our findings suggest that the therapeutic effect of NXSBD containing serum in ITP mice may be attributed to its upregulation of miR-199a-5p in BMSCs-Exo, which contributes to modulating the immune balance of CD4
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