Evidence mapPaperPMID 41693808Full record

ArticleOphthalmology science2026

The Association of Lapses in Diabetic Retinopathy Care with Vision Impairment.

Gina Zhu, Erik Westlund, Diep Tran, Cindy X Cai

Abstract read
In one paragraph

Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gina ZhuWilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.
Erik WestlundDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Diep TranWilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.
Cindy X CaiWilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.

Funding

Impact of Social Determinants of Health in Diabetic RetinopathyK23EY033440 · JOHNS HOPKINS UNIVERSITY · 2025 to 2025
$189k
NEI NIH HHS K23 EY033440
6 · The paper itself

Abstract

Objective: To identify the association of lapses in diabetic retinopathy (DR) care with vision impairment among patients with type 2 diabetes (T2D), stratified by DR severity and treatment status. Design: Retrospective cohort study. Subjects: Adults with T2D seen at the Wilmer Eye Institute from 2013 to 2023. Methods: Propensity score modeling was used to estimate the probability that a patient would experience a lapse in care during a 2-year observation window based on sociodemographic (age, sex, self-reported race or ethnicity, insurance), ocular (baseline visual acuity, ophthalmic comorbidities, history of retinal treatments), and medical factors (Diabetes Complication Severity Index, Charlson Comorbidity Index). Doubly robust logistic regression models using inverse probability weighting of the propensity scores were used to estimate the association of care lapses with vision impairment. We also estimated average marginal effects to examine the probability difference in vision impairment associated with care lapses among patients grouped by DR severity (no DR, nonproliferative DR, proliferative DR) and treatment status (no treatment, any treatment, anti-VEGF only, panretinal photocoagulation only). Main Outcome Measures: Vision impairment (or vision worse than Snellen equivalent 20/40) at the end of the observation period. Results: A total of 45 764 patients with 90 440 eyes contributed to the study. Most patients were female (52%), and the average age was 61.7 years. A total of 81% had a lapse in care. Patients who had a lapse in care had 50% higher odds of having vision impairment compared with patients who never lapsed ( Conclusions: For patients with T2D, a lapse in care was associated with higher odds of having vision impairment, regardless of underlying severity of DR or treatment status. These findings highlight the importance of longitudinal DR care and reducing lapses in care to prevent vision loss. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

Diabetic retinopathyLapses in careVision impairment

Identifiers

PMID41693808
PMCPMC12902142

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.