Evidence map›Paper›PMID 41693925›Full record

ArticleAdvanced materials technologies2025

Multiplexed luminal tissue constructs with reconfigurable barriers for dynamic modeling of multi-tissue interactions.

Mouhita Humayun, José A Jiménez-Torres, Chao Li, Jose Ayuso, Karina Lugo Cintron, Joseph Ulbrich, Benjamin Myers, Sheena C Kerr, Adeel Ahmed, David J Beebe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials technologies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mouhita HumayunDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
José A Jiménez-TorresDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Chao LiCarbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA.
Jose AyusoDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Karina Lugo CintronDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Joseph UlbrichDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Benjamin MyersDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Sheena C KerrCarbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA.
Adeel AhmedCarbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA.
David J BeebeDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Project 3: Modulation of the head and neck tumor immune microenvironment by targeting the TAM family of receptorsP50CA278595 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI David J Beebe · 2022 to 2026
$12.5M
University of Wisconsin Prostate SPOREP50CA269011 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI DAVID F. JARRARD, DOUGLAS G. MCNEEL · 2023 to 2026
$10.6M
Under-oil open microfluidic system (UOMS) for studying systemic fungal infectionR01AI154940 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J, MCCLEAN, MEGAN N · 2021 to 2025
$3.8M
An automated high-throughput tissue model for screening metastatic effectorsR01CA186134 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J · 2015 to 2019
$3.1M
Development of a human intestinal microphysiological system for the study of immune responses to protozoan parasitesR01AI172874 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI David J Beebe, LAURA J KNOLL · 2023 to 2026
$3.1M
A multiplexed micro scale assay for real time analysis of pediatric immune cell functionU24AI152177 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J, KERR, SHEENA CATHERINE · 2020 to 2024
$1.8M
Targeting cancer-stroma interactions in breast cancer metastasis using organotypic modelingF31CA247248 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI HUMAYUN, MOUHITA · 2019 to 2021
$67k
NCI NIH HHS F31 CA247248NCI NIH HHS P30 CA014520NCI NIH HHS P50 CA269011NCI NIH HHS P50 CA278595NCI NIH HHS R01 CA186134NIAID NIH HHS R01 AI154940NIAID NIH HHS R01 AI172874NIAID NIH HHS U24 AI152177
6 · The paper itself

Abstract

Cell-lined luminal structures are crucial for nutrient transport, tissue barriers, and paracrine interactions. Modeling these structures is essential for developing accurate

Indexed as

biofabricationbiomaterials and biomedical engineeringdynamic reconfigurable interactionshigher-throughputluminal tissuesmicrophysiological systemsorgans-on-chips

Identifiers

PMID41693925
PMCPMC12900169

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.