Evidence map›Paper›PMID 41694493›Full record

ArticleWorld journal of gastroenterology2026

Endoscopic ultrasound in early gastric cancer: Diagnostic accuracy and Tis/T1a lesion over staging risks.

Xue-Yan Qiao, Ze-Hua Li, Shi-Yong Lin, Ge Wen

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Article in World journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xue-Yan QiaoDepartment of Medical Imaging, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Ze-Hua LiDepartment of Endoscopy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou 510050, Guangdong Province, China.
Shi-Yong LinDepartment of Endoscopy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou 510050, Guangdong Province, China.
Ge WenDepartment of Medical Imaging, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China. wenge@smu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate T-staging of early gastric cancer (EGC) is critical for selecting the most appropriate treatment strategy. Although the reported diagnostic performance of endoscopic ultrasound (EUS) in determining T stage varies among studies, it continues to serve as an important tool in the pretreatment assessment of EGC.

aimTo identify clinicopathological factors that affect the diagnostic accuracy of EUS in EGC, with particular emphasis on mucosal lesions (Tis/T1a).

methodsWe included EGC patients who underwent endoscopic resection or gastrectomy. The diagnostic accuracy of EUS was assessed by comparing its T-stage evaluation with the histopathological results of the resected specimens. Additionally, potential risk factors associated with the over staging of Tis/T1a lesions by EUS were investigated.

resultsA total of 209 patients were included in this study. The overall diagnostic accuracy of EUS for T staging was 74.64%. However, the sensitivity of EUS in identifying Tis/T1a gastric cancers was relatively low at 41.25%. Risk factor analysis showed that younger age (

conclusionThe accuracy of EUS for staging Tis/T1a early gastric cancer is markedly reduced when gastric ulceration is present. Therefore, EUS-based staging should be interpreted cautiously in patients with ulcer-related lesions.

Indexed as

EndosonographyStomach NeoplasmsAdultAgedAged, 80 and overAge FactorsEarly Detection of CancerFemaleGastrectomyGastric MucosaGastroscopyHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesDiagnostic accuracyEarly gastric cancerEndoscopic ultrasoundOver stagingTumor staging

Identifiers

PMID41694493
PMCPMC12898096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.