ArticleJPGN reports2026
Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunity.
Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Review
- Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunity.JPGN reports · 2026Article
- Pediatric celiac disease and coexisting immune-mediated conditions: a five-year single-center study from North-Eastern Romania.Frontiers in pediatrics · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Objective: To determine if multiplex autoantibody arrays can identify novel biomarker signatures in children with one or multiple autoimmune diseases (polyautoimmunity). Methods: Plasma collected from children (18 years or younger) in the Boston Children's Hospital Precision Link Biobank for Health Discovery between January 2007 and June 2021 was analyzed using a microarray with 120 autoantigens associated with various autoimmune diseases to assess for both immunoglobulin G (IgG) and A (IgA) autoantibodies. To determine if disease-specific, we binary classified those with polyautoimmunity and the most common autoimmune diseases in our cohort (autoimmune thyroid disease, type 1 diabetes, or celiac disease [CeD]). For each comparison within and between groups, the autoantibody intensity was releveled to the control and a linear model was fit. Results: Plasma was analyzed from 114 children with either CeD ( Conclusions: Use of multiplex antigen arrays in patients with and without polyautoimmunity is a valuable tool to identify known and potentially novel disease-antigens. Further study is needed to determine the role of H/K ATPase autoantibodies in monitoring of CeD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.