Evidence map›Paper›PMID 41696104›Full record

ArticleWorld journal of diabetes2026

Using the triglyceride-glucose index and derived indexes to forecast progression from pre-diabetes to diabetes: A 3-year follow-up study.

Bing Wang, Ming-Chuan Liu, Xu-Han Liu, Zhu Zhu, Ying-Shu Liu, Ting-Ting Zhang, Xin-Yu Li, Zheng-Nan Gao

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Article in World journal of diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Bing WangDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China.
Ming-Chuan LiuGraduate School, Dalian Medical University, Dalian 116044, Liaoning Province, China.
Xu-Han LiuDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China.
Zhu ZhuDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China.
Ying-Shu LiuDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China.
Ting-Ting ZhangDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China.
Xin-Yu LiDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China.
Zheng-Nan GaoDepartment of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian 116033, Liaoning Province, China. gao2008@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-diabetes is a transitional metabolic stage between health and diabetes, serving as a critical warning signal for disease progression. Early intervention targeting risk factors in prediabetic individuals prevents the progression to type 2 diabetes.

aimTo investigate the predictive value of the triglyceride-glucose (TyG) index and its derived indicators for new-onset diabetes in patients with pre-diabetes.

methodsA prospective community-based cohort study was carried out based on subjects aged over 40 years with pre-diabetes in Dalian, Liaoning Province, China. A total of 1352 subjects with complete follow-up data attended the follow-up survey. Multivariable Cox regression models were performed to assess the association of the TyG index and its derived indicators with risk of diabetes in patients with pre-diabetes. The diagnostic values of the TyG index and derived indicators in predicting new-onset diabetes were analyzed, and suitable cutting points were determined using the receiver operating characteristic (ROC) curve.

resultsDuring a 3-year follow-up period, 153 cases with incident diabetes were identified, with a cumulative incidence of diabetes of 11.3%; 12.6% (43/341) in males and 10.9% (110/1011) in females (

conclusionThe TyG index and its derived indicators were risk factors for the pre-diabetes to diabetes outcome, and may be regarded as predictors of the outcome. The risk of conversion of pre-diabetes to diabetes increased with increases in the TyG index and its derived indicators. The TyG-BMI was better than TyG and TyG-WC in predicting the 3-year outcome for diabetes. Although these indices could aid in the initial risk stratification in primary care, their modest accuracy warrants cautious interpretation.

Indexed as

DiabetesPre-diabetesProspective cohort studyTriglyceride-glucose-body mass indexTriglyceride-glucose indexTriglyceride-glucose-waist circumference index

Identifiers

PMID41696104
PMCPMC12897390

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.