Evidence map›Paper›PMID 41696259›Full record

ArticleACS omega2026

3D Printing of Hydrophobic API-Infused Alginate-Gelatin Porous Scaffolds Reinforced with TiO

Rodrigo Urruela-Barrios, Josué García-Ávila, Alejandro J Alvarez, Wendy Ortega-Lara, Erick Ramírez-Cedillo

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rodrigo Urruela-BarriosTecnologico de Monterrey, School of Engineering and Sciences, Ave. Eugenio Garza Sada #2501 Sur, Col. Tecnológico, Monterrey 64700, N.L., Mexico.
Josué García-ÁvilaDepartment of Mechanical Engineering, Columbia University, New York City, New York 10027, United States.
Alejandro J AlvarezTecnologico de Monterrey, School of Engineering and Sciences, Ave. Eugenio Garza Sada #2501 Sur, Col. Tecnológico, Monterrey 64700, N.L., Mexico.ORCID https://orcid.org/0000-0002-8662-2374
Wendy Ortega-LaraTecnologico de Monterrey, School of Engineering and Sciences, Ave. Eugenio Garza Sada #2501 Sur, Col. Tecnológico, Monterrey 64700, N.L., Mexico.ORCID https://orcid.org/0000-0002-8536-158X
Erick Ramírez-CedilloTecnologico de Monterrey, School of Engineering and Sciences, Ave. Eugenio Garza Sada #2501 Sur, Col. Tecnológico, Monterrey 64700, N.L., Mexico.ORCID https://orcid.org/0000-0001-5137-4510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scaffolds in tissue engineering and regenerative medicine have demonstrated improved functionality when loaded with pharmaceutical active ingredients (APIs). However, few systematic and energy-efficient methodologies allow controllable drug loading, particularly for hydrophobic compounds. This study presents a novel and controllable approach for loading 3D-printed alginate/gelatin hydrogel scaffolds with hydrophobic ibuprofen. The scaffold, composed mainly of alginate biopolymer, is nontoxic, biocompatible, and highly porous, allowing APIs to be easily incorporated within its structure. Owing to the ease of alginate gelation, microextrusion 3D printing was used to fabricate these hydrogel-based scaffolds. Reinforcing agents, including TiO

Identifiers

PMID41696259
PMCPMC12902847

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.