Evidence map›Paper›PMID 41696806›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

Vascular basement membrane laminins modulate functional zonation of cerebral microvessels.

Tushar Deshpande, Kishan Kapupara, Melanie-Jane Hannocks, Jula Huppert, Sai-Kiran Samawar, Devika Rag Thulichery, Sigmund Budny, Sharang Ghavampour, Jian Song, Lingzhang Meng and 7 more

Abstract read
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In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tushar DeshpandeInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Kishan KapuparaInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.ORCID 0000-0002-0463-9050
Melanie-Jane HannocksInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.ORCID 0000-0002-9958-4928
Jula HuppertInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Sai-Kiran SamawarInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Devika Rag ThulicheryInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.ORCID 0009-0002-7707-8503
Sigmund BudnyInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Sharang GhavampourInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Jian SongInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Lingzhang MengInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Ralf H AdamsDepartment of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine, Muenster, Germany.ORCID 0000-0003-3031-7677
Hyun-Woo JeongDepartment of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine, Muenster, Germany.
Lydia WachsmuthClinic of Radiology, University of Muenster, Muenster, Germany.
Cornelius FaberClinic of Radiology, University of Muenster, Muenster, Germany.
Jens SoltwischInstitute of Hygiene, University of Muenster, Muenster, Germany.
Rupert HallmannInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.
Lydia SorokinInstitute of Physiological Chemistry and Pathobiochemistry, Cells in Motion Interfaculty Centre (CiMIC), University of Muenster, Muenster, Germany.ORCID 0000-0001-7704-7921

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether basement membrane (BM) laminins influence regional differences in the vasculature by performing single-cell RNA sequencing on cerebral blood vessels from mice lacking the major vascular laminins in endothelial and smooth muscle BMs, laminin α4 (

Indexed as

Basement MembraneLamininMicrovesselsAnimalsEndothelial CellsMiceMice, KnockoutStrokeLama4 protein, mouseLamininlaminin alpha5basement membrane lamininsmural cellsscRNA-seqstroke (tMCAO)Vascular zonation

Identifiers

PMID41696806
PMCPMC12913041

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.