Trial reportThe Journal of international medical research2026
Postoperative continuous infusion of dexmedetomidine does not improve gastrointestinal function recovery after laparoscopic colorectal surgery: A randomized clinical trial.
Trial report in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dexmedetomidine and Postoperative Gastrointestinal Recovery: A Critical Narrative Review of Direct Enteric and Opioid-Sparing Pathways.Drug design, development and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectivesThis study aimed to investigate the effect of postoperative dexmedetomidine infusion on the recovery of gastrointestinal function in patients undergoing laparoscopic colorectal surgery.MethodsA total of 128 participants were randomized into dexmedetomidine and control groups. In the dexmedetomidine group, patients received a loading dose of 0.5 μg/kg dexmedetomidine over 15 min before skin incision followed by continuous infusion of 0.05 μg/kg/h starting at the end of surgery and maintained for 48 h. The control group received the same loading dose of dexmedetomidine without the postoperative infusion.ResultsNo statistically significant differences were observed between the dexmedetomidine and control groups in time to first flatus, time to first defecation, or time to first oral feeding. The incidences of postoperative gastrointestinal function and delirium were comparable between the two groups. However, patients in the dexmedetomidine group experienced better sleep quality and had lower C-reactive protein levels than those in the control group.ConclusionsAlthough postoperative continuous infusion of dexmedetomidine was associated with improved sleep quality in patients undergoing laparoscopic colorectal surgery, it did not accelerate the recovery of gastrointestinal function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.