ArticleScientific reports2026
Novel sterol-spiropyran derivatives: synthesis and photoactivity in Langmuir monolayers.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Amphiphilic Baskets for Supramolecular Nanoarchitectures at Interfaces: Inverted Monolayer Formation on Water.Langmuir : the ACS journal of surfaces and colloids · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe the synthesis of novel sterol-spiropyran conjugates based on either cholesterol or ergosterol and designed to easily incorporate in lipid membranes. We demonstrate that these compounds, in mixtures with a lipid, form stable and light-responsive Langmuir monolayers on aqueous surfaces. Large differences in the monolayer pressure-area isotherms are observed upon light-induced conformational switch of the spiropyran moiety of the sterol-spiropyran compound in the monolayer. We present evidence that the kinetics of monolayer response to photoisomerisation is controlled by the monolayer compressional (dilatational) elasticity. The results suggest that these sterol-spiropyran conjugates would likely readily incorporate in more complex lipid systems such as bilayers and could provide a coupling mechanism to control their properties, lateral organisation and morphology by light.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.