Evidence map›Paper›PMID 41699282›Full record

Observational studyEuropean journal of nuclear medicine and molecular imaging2026

Collagen-binding probe PET/MR for distinguishing fibrotic from inflammatory strictures in Crohn's disease.

Antonino Andrea Blandino, Peter Caravan, Rocco Ricciardi, Liliana G Bordeianou, Hiroko Kunitake, Robert N Goldstone, Michael G Drage, M Lisa Zhang, Ashwin N Ananthakrishnan, Onofrio Antonio Catalano

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06252493 (Evaluation of PET/MR Enterography for Differentiation of Fibrotic and Inflammatory Strictures in Patients With Crohn's Disease Using a Collagen-binding Radiotracer.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06252493 recruitingnot on this map

Evaluation of PET/MR Enterography for Differentiation of Fibrotic and Inflammatory Strictures in Patients With Crohn's Disease Using a Collagen-binding Radiotracer.

TypeobservationalSponsorMassachusetts General HospitalRan2023 to 2029Enrolled25ConditionsCrohn DiseaseArmsRadiotracer Injection, Contrast Media, Magnetic Resonance, Blood Draw, Glucagon, Imaging
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antonino Andrea BlandinoDepartment of Radiology, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.ORCID 0009-0004-6017-5467
Peter CaravanDepartment of Radiology, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.ORCID 0000-0002-3179-6537
Rocco RicciardiDepartment of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Liliana G BordeianouDepartment of Surgery, Massachusetts General Hospital, Colorectal Surgery Program, Boston, MA, USA.
Hiroko KunitakeDepartment of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Robert N GoldstoneDepartment of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Michael G DrageDepartment of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0003-2593-8268
M Lisa ZhangDepartment of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-8029-4787
Ashwin N AnanthakrishnanDivision of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-9436-1821
Onofrio Antonio CatalanoDivision of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Radiology Administration, WHT 270, Boston, MA, 02114, USA. onofriocatalano@yahoo.it.ORCID 0000-0001-7733-4138

Funding

Takeda Pharmaceuticals U.S.A. Takeda Pharmaceuticals U.S.A.
6 · The paper itself

Abstract

purposeTo evaluate the feasibility and diagnostic performance of MATERIALS AND

methodsPatients with stricturing Crohn's disease scheduled for bowel resection or endoscopic biopsy were prospectively enrolled. PET/MR enterography was performed after intravenous administration of

resultsFive patients (4 M, 1 F; median age: 50; IQR: 11) with seven strictured bowel segments (median length: 24 mm; IQR: 14) were included. Five segments (71.4%) demonstrated focal

conclusion

trial registrationClinicalTrials.gov, NCT06252493. Date of first enrollment: 19 December 2023. Registered: 2 February 2024 (retrospectively registered).

Indexed as

CollagenCrohn DiseaseMagnetic Resonance ImagingMultimodal ImagingPositron-Emission TomographyAdultConstriction, PathologicDiagnosis, DifferentialFemaleFibrosisGallium RadioisotopesHumansInflammationMaleMiddle AgedCollagenGallium Radioisotopes68Ga-CBP8Bowel fibrosisCrohn’s diseaseIBDIntestinal stricturesPET/MR enterography

Identifiers

PMID41699282

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.