Evidence map›Paper›PMID 41699474›Full record

ArticleBMC cardiovascular disorders2026

Antihypertensive medication adherence and associated risk factors among adults with hypertension: a cross-sectional study in a teaching hospital, Ghana.

Oksana Ryabinina, Francis Ohene Addo, Nicholas Ekow Thomford, Francis Zumesew, Alexandra Adjakie Debrah, Paul Nsiah, Isabel Oduro-Boateng, Nasara Umaimah Abubakar Sadiq, Raji Sakibu Abdul, Reindoff Junior Ofori-Atta and 1 more

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Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Oksana RyabininaDepartment of Chemical Pathology, School of Medical Sciences, College of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana. oksana.debrah@ucc.edu.gh.
Francis Ohene AddoDepartment of Chemical Pathology, School of Medical Sciences, College of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Nicholas Ekow ThomfordPharmacogenomics and Genomic Medicine Group, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Francis ZumesewDepartment of Chemical Pathology, School of Medical Sciences, College of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Alexandra Adjakie DebrahSchool of Pharmacy, College of Health Sciences, University of Ghana, Accra, Ghana.
Paul NsiahDepartment of Chemical Pathology, School of Medical Sciences, College of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Isabel Oduro-BoatengCenter for Research in Applied Biology, University of Energy and Natural Resources, Sunyani, Ghana.
Nasara Umaimah Abubakar SadiqCenter for Research in Applied Biology, University of Energy and Natural Resources, Sunyani, Ghana.
Raji Sakibu AbdulCenter for Research in Applied Biology, University of Energy and Natural Resources, Sunyani, Ghana.
Reindoff Junior Ofori-AttaCenter for Research in Applied Biology, University of Energy and Natural Resources, Sunyani, Ghana.
Emmanuel Timmy DonkohCenter for Research in Applied Biology, University of Energy and Natural Resources, Sunyani, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension remains a significant public health challenge worldwide, with an estimated 1.28 billion adults aged 30-79 years affected, two-thirds of whom reside in low- and middle-income countries. It accounts for approximately 12.8% of global mortality, and in Ghana, hypertension-induced deaths constitute about 5.2% of total mortality. One of the major challenges in hypertension management is poor adherence to antihypertensive medications, which can lead to uncontrolled blood pressure and an increased risk of complications. This study assessed medication adherence rates and predictors among patients attending the hypertension clinic at Cape Coast Teaching Hospital (CCTH) in Ghana.

methodsA cross-sectional study was conducted among 292 participants receiving care at the hypertension clinic at CCTH. Data on sociodemographic characteristics and medication adherence were collected using a semi-structured electronic questionnaire. Additionally, anthropometric measurements, systolic and diastolic blood pressure readings were recorded for all participants.

resultsThe mean age of the study participants was 63.1 years (SD ± 11.0), with 77.7% being female. The majority of participants were married or cohabiting (66.3%), self-employed (40.9%), and had at least a tertiary level of education (37.5%). The overall medication adherence rate was 67.8%. In multivariable logistic regression, ethnicity (non-Akan, aOR = 3.52, p = 0.02), regular blood pressure monitoring (aOR = 1.853, p = 0.012), knowledge of medications (aOR = 4.395, p < 0.001), dosage schedules (aOR = 5.274, p < 0.001) and medication availability (aOR = 4.156, p = 0.001) were significant predictors of antihypertensive medication adherence.

conclusionThe study revealed a moderately high adherence rate among participants. Continuous efforts to improve drug adherence regular by promoting significant predictors of adherence such as regular BP monitoring, medication availability and other patient-friendly measures are warranted.

Indexed as

Antihypertensive AgentsBlood PressureHospitals, TeachingHypertensionMedication AdherenceAdultAgedCross-Sectional StudiesFemaleGhanaHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedRisk FactorsAntihypertensive AgentsBlood pressureDrug adherenceGhanaHypertension

Identifiers

PMID41699474
PMCPMC12908267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.