Evidence map›Paper›PMID 41699512›Full record

ReviewBMC pregnancy and childbirth2026

Successful conservative management of placenta accreta spectrum in Ethiopia: a case report and literature review.

Abraham Abebe, Getachew Ayana, Melkamu Siferih

Abstract readCase ReportsReview
In one paragraph

Review in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abraham AbebeDepartment of Obstetrics and Gynecology, Assosa General Hospital, Assosa, Benishangul-Gumuz Region, Ethiopia.
Getachew AyanaDepartment of Obstetrics and Gynecology, Assosa General Hospital, Assosa, Benishangul-Gumuz Region, Ethiopia.
Melkamu SiferihDepartment of Obstetrics and Gynecology, School of Medicine, Debre Markos University, Debre Markos, Amhara Region, Ethiopia. melkamu.siferih@dmu.edu.et.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlacenta accreta spectrum (PAS) is a leading cause of catastrophic obstetric hemorrhage. Although cesarean hysterectomy is the standard approach, conservative management is increasingly used to preserve fertility. Evidence from Sub-Saharan Africa remains limited, however. We report a rare Ethiopian case of PAS managed conservatively without hysterectomy and provide a brief review of similar strategies in the literature to contextualize this case. CASE PRESENTATION: A 20-year-old woman (gravida 2 para 1) with no prior uterine surgery underwent cesarean section for prolonged prelabor rupture of membranes and breech presentation at 37 + 2 weeks’ gestation. Intraoperatively, a highly vascular fundal mass extending to the left adnexa suggested PAS. Attempts at placental removal were unsuccessful, but bleeding remained minimal. To preserve fertility, and because advanced PAS surgical management was not available, a conservative approach was adopted and the placenta was left in situ. Postoperative management included antibiotics, uterotonics, and serial methotrexate. The placenta gradually regressed without hemorrhage, sepsis, or need for secondary surgery. At three-year follow-up, the woman remained stable with normal menstruation and intact uterus.

conclusionsPlacenta in situ management—supported by structured monitoring and methotrexate—can be a safe and feasible option in carefully selected women with PAS, even in low-resource settings. It provides rare, regionally relevant evidence and underscores the need for context-specific PAS protocol to expand fertility- preserving management options where surgical capacity is limited.

Indexed as

Conservative TreatmentPlacenta AccretaAnti-Bacterial AgentsCesarean SectionEthiopiaFemaleFertility PreservationHumansMethotrexateOxytocicsPregnancyYoung AdultAnti-Bacterial AgentsMethotrexateOxytocicsCase reportConservative managementEthiopiaPlacenta accreta spectrumPlacenta left in situ

Identifiers

PMID41699512
PMCPMC13011532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.