Evidence map›Paper›PMID 41700829›Full record

ArticleMicrobiology spectrum2026

Glutamate metabolism: an essential component for persistence in

George W Liechti

Abstract readComment
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Comment on
    2025
5 · Who and what money

Authors and funding

1 author.

George W LiechtiDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA.ORCID 0000-0003-3028-8474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virulence determinants, immune evasion strategies, and antibacterial tolerance/resistance mechanisms are often presented as hallmarks of bacterial pathogenesis. Behind each of these morbific features, there exist fundamental metabolic pathways that enable the local environment to define and shape their utilization. In a recent study, X. Wen, T. Tang, T. Bao, T. Xu, et al. (Microbiol Spectr 13:e00511-25, 2025, https://doi.org/10.1128/spectrum.00511-25) investigated how glutamate availability directly influences persister formation in

Indexed as

Glutamic AcidStaphylococcal InfectionsStaphylococcus aureusAnimalsAnti-Bacterial AgentsBacterial ProteinsBiofilmsGlutamate SynthaseMetabolic Networks and PathwaysOxidative StressAnti-Bacterial AgentsBacterial ProteinsGlutamate SynthaseGlutamic Acidglutamate synthasepersistenceStaphylococcus aureus

Identifiers

PMID41700829
PMCPMC13055227

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.