Evidence map›Paper›PMID 41701636›Full record

ArticleVirulence2026

The cyclin dependent kinase (CDK)7 inhibitor BS-181 inhibits pathogenic Cryptococcus species, causing G

Pooja Sethiya, Desmarini Desmarini, Bethany Bowring, Hue Dinh, Amy K Cain, Chirag Parsania, Catriona L Halliday, Sharon C-A Chen, Kim Hewitt, Julianne Teresa Djordjevic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pooja SethiyaCentre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.
Desmarini DesmariniCentre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.
Bethany BowringCentre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.
Hue DinhARC Centre of Excellence in Synthetic Biology, School of Natural Sciences, Macquarie University, North Ryde, NSW, Australia.
Amy K CainARC Centre of Excellence in Synthetic Biology, School of Natural Sciences, Macquarie University, North Ryde, NSW, Australia.
Chirag ParsaniaCancer & Gene Regulation Laboratory Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.
Catriona L HallidaySydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia.
Sharon C-A ChenSydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia.
Kim HewittWestmead Bioresources Facility and Scientific Platforms, Westmead Institute for Medical Research, Westmead, NSW, Australia.
Julianne Teresa DjordjevicCentre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.ORCID 0000-0003-4207-4115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fungal priority pathogen and basidiomycete,

Indexed as

Antifungal AgentsCryptococcus gattiiCryptococcus neoformansCyclin-Dependent KinasesPyrimidinesRNA SplicingAnimalsCryptococcosisCyclin-Dependent Kinase-Activating KinaseFemaleHumansMiceMicrobial Sensitivity TestsAntifungal AgentsCyclin-Dependent Kinase-Activating KinaseCyclin-Dependent KinasesPyrimidinesantifungalBS-181CDK7 inhibitorcell cycleCryptococcus gattiiCryptococcus neoformanssplicingtranscriptiontranslation

Identifiers

PMID41701636
PMCPMC12915825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.