Evidence map›Paper›PMID 41701825›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A sterility-associated long noncoding RNA involved in honey bee caste determination and adult queen and worker fertility.

Carlos A M Cardoso-Júnior, Gustavo J Tibério, Marina C Peruzzolo, Luiz C Vieira, Denyse C Lago, Alexandre R Paschoal, Isobel Ronai, Benjamin P Oldroyd, Klaus Hartfelder

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlos A M Cardoso-Júnior *Departamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14049-900, Brazil.ORCID 0000-0002-5039-8358
Gustavo J Tibério *Departamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14049-900, Brazil.
Marina C PeruzzoloDepartamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14049-900, Brazil.
Luiz C VieiraDepartamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14049-900, Brazil.
Denyse C LagoDepartamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14049-900, Brazil.
Alexandre R PaschoalDepartamento Acadêmico de Computação, Universidade Tecnológica Federal do Paraná, Cornélio Procópio, PR 86300-000, Brazil.
Isobel RonaiBehaviour, Ecology and Evolution Laboratory, School of Life and Environmental Sciences, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-1658-857X
Benjamin P OldroydBehaviour, Ecology and Evolution Laboratory, School of Life and Environmental Sciences, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0001-6831-3677
Klaus HartfelderDepartamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP 14049-900, Brazil.ORCID 0000-0001-7981-8427

Funding

Australian Research Council Centre of Excellence in Advanced Molecular Imaging (Imaging CoE) DP180101696Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 440412/2022-6Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 001Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2011/15810-2Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2014/05757-5Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2016/15881-0Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2016/16622-9Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2017/09128-0Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2017/09269-3Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2019/07264-0Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2020/08524-2
6 · The paper itself

Abstract

Insect sociality is a major evolutionary transition based on the suppression of worker reproduction in favor of a queen's reproductive monopoly. Although sophisticated insect societies have arisen independently on multiple occasions in the Hymenoptera (bees, ants, and wasps), how worker sterility evolved through natural selection is not fully understood. In honey bees (

Indexed as

RNA, Long NoncodingAnimalsBeesFemaleFertilityJuvenile HormonesLarvaOvaryReproductionSocial BehaviorJuvenile HormonesRNA, Long Noncodingeusocialitykin selectionpolyphenismreproductive altruismsociobiology

Identifiers

PMID41701825
PMCPMC12933031

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.