Influences of dietary guanidinoacetic acid supplementation on performance and proteins involved in milk fat and protein synthesis in dairy cows.

Jing Zhang, Yanchu Tang, Changjian Xue, Jiaojiao Lang, Wenjie Huo, Caixia Pei, Qiang Liu

Abstract read

In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jing ZhangCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Yanchu TangCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Changjian XueCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Jiaojiao LangCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Wenjie HuoCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Caixia PeiCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Qiang LiuCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guanidinoacetic acid (GAA) increases milk production in dairy cows by promoting milk fatty acid (FA) and protein synthesis; however, its mechanism is unclear. It was hypothesized that provision of rumen-protected GAA (RPGAA) would increase milk production, and milk fat and protein synthesis, while revealing the underlying mechanisms. Forty-four multiparous Holstein dairy cows (33.5 ± 1.31 kg/d of milk yield, 667 ± 11.8 kg of body weight, and 38.5 ± 2.14 d in milk [DIM]) were blocked by daily milk yield and DIM, and allocated to different treatments in a randomized-block design, namely, the control (without RPGAA), low-RPGAA (0.18 g/kg DM of GAA), medium-RPGAA (0.36 g/kg DM of GAA), and high-RPGAA (0.54 g/kg DM of GAA) groups. The experiment lasted for 95 d, including a 10-d covariate period, a 15-d adaptation period, and a 70-d sampling period. Although the DM intake and BW were not impacted (

Indexed as

Guanidinoacetic acidMammary glandMilk fatty acidMilk performanceMilk proteinNutrient digestibility

Identifiers

PMID41704252

DOI10.1016/j.aninu.2025.07.008

PMCPMC12907830

What Socratic holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.