ArticleInnovative surgical sciences2026
Interdisciplinary therapy of extremity soft tissue sarcomas: current evidence on systemic treatments and the role of reconstructive surgery.
Article in Innovative surgical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Optimising Clinical Outcomes Following R1 Resection in Soft Tissue Sarcoma: An Evidence-Based Approach.Current treatment options in oncology · 2026Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Soft tissue sarcomas are rare and heterogenous tumors, that often pose diagnostic and therapeutic challenges. Guideline-compliant therapy includes surgical resection with negative margins, supplementary radiotherapy and, if necessary, accompanied by systemic therapy. Diagnostic and therapeutic approaches should be discussed and planned in an interdisciplinary oncological conference. The aim of this article is to provide an overview of guideline-based interdisciplinary therapeutic options, limitations and prospects. An exemplary case is used to illustrate interdisciplinary concepts. Case Presentation: A six-year-old girl with a locally advanced epithelioid sarcoma of the right hand was recommended to receive a hand amputation. Due to a request for limb-preservation, the patient presented at various sarcoma centers and initially received neoadjuvant radiotherapy. This resulted in a reduction of the tumor mass so that a tumor resection could subsequently be performed. Despite pronounced local findings, microscopically negative margins and a satisfactory postoperative result in hand function were achieved. Conclusions: This case highlights the critical role of interdisciplinary collaboration and centralized care in the treatment of soft tissue sarcomas. Plastic reconstructive surgery enables radical oncological resection while preserving function, especially in anatomically complex cases. Early referral to a specialized sarcoma center and adherence to current guidelines (e.g., ESMO-EURACAN-GENTURIS) are essential to achieving optimal oncological and functional outcomes.
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Registered trials
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