Evidence mapPaperPMID 41704476Full record

ArticleJBMR plus2026

Femora from adults with type 1 or type 2 diabetes have lower bone strength and smaller hip geometry.

Shannon R Emerzian, Fjola Johannesdottir, David C Lee, I-Hsien Wu, Surya Vishva Teja Jangolla, Marc Gregory Yu, Hetal S Shah, George L King, Tony M Keaveny, Klaus Engelke and 2 more

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shannon R EmerzianDepartment of Orthopedic Surgery, Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States.ORCID https://orcid.org/0000-0002-1085-4128
Fjola JohannesdottirDepartment of Orthopedic Surgery, Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States.ORCID https://orcid.org/0000-0003-3054-9152
David C LeeO.N. Diagnostics, Berkeley, CA, 94704, United States.ORCID https://orcid.org/0009-0006-4486-331X
I-Hsien WuResearch Division, Joslin Diabetes Center, Boston, MA 02215, United States.ORCID https://orcid.org/0000-0002-2563-7505
Surya Vishva Teja JangollaResearch Division, Joslin Diabetes Center, Boston, MA 02215, United States.
Marc Gregory YuResearch Division, Joslin Diabetes Center, Boston, MA 02215, United States.
Hetal S ShahResearch Division, Joslin Diabetes Center, Boston, MA 02215, United States.
George L KingResearch Division, Joslin Diabetes Center, Boston, MA 02215, United States.ORCID https://orcid.org/0000-0002-0335-5881
Tony M KeavenyO.N. Diagnostics, Berkeley, CA, 94704, United States.ORCID https://orcid.org/0000-0003-0258-7178
Klaus EngelkeInstitute of Medical Physics, University of Erlangen-Nürnberg, Erlangen, 91052, Germany.ORCID https://orcid.org/0000-0001-9875-4123
Elaine W YuEndocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States.
Mary L BouxseinDepartment of Orthopedic Surgery, Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States.ORCID https://orcid.org/0000-0002-7027-7414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increased hip fracture risk in individuals with type 1 (T1D) and type 2 (T2D) diabetes is not explained by areal BMD (aBMD), indicating that diabetes increases fracture risk through mechanisms independent of aBMD. To investigate, we used QCT to compare femoral strength, volumetric BMD (vBMD), and geometry in cadaveric femora from older adults with T1D (

Indexed as

BMDbone strengthbone structurefinite element analysisQCTtype 1 diabetestype 2 diabetes

Identifiers

PMID41704476
PMCPMC12908684

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.