Evidence map›Paper›PMID 41704797›Full record

ArticleResearch and practice in thrombosis and haemostasis2026

Patient-reported outcomes after upper-extremity deep vein thrombosis due to compression syndromes: a multinational longitudinal retrospective study.

Maya Abrishami Kashani, Domenico Baccellieri, Mert Dumantepe, Naomi Elbaranes, Nicolas Gendron, Marianna Gigliotti De Fazio, Egidio Imbalzano, Lina Khider, Nils Kucher, Corrado Lodigiani and 6 more

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Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Maya Abrishami KashaniDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.
Domenico BaccellieriVascular Surgery Department, IRCCS H. San Raffaele, Milan, Italy.
Mert DumantepeDepartment of Cardiovascular Surgery, Uskudar University School of Medicine, Istanbul, Turkey.
Naomi ElbaranesDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.
Nicolas GendronHematology Department, Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris-Centre Université Paris Cité (APHP-CUP), F-75015 Paris, France.
Marianna Gigliotti De FazioDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Egidio ImbalzanoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Lina KhiderParis Cité University, INSERM, Paris Cardiovascular Research Centre, Team Endotheliopathy and Hemostasis Disorders, Paris, France.
Nils KucherDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.
Corrado LodigianiIRCCS Humanitas Research Hospital, Center for Thrombosis and Hemorrhagic Diseases.
Benedetta MadaroDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.
Saskia MiddeldorpDepartment of Internal Medicine, Radboud university medical center, Nijmegen, Netherlands.
Clara SaccoIRCCS Humanitas Research Hospital, Center for Thrombosis and Hemorrhagic Diseases.
Yasmine TerbecheVascular Medicine Department, Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris-Centre Université Paris Cité (APHP-CUP), Paris, France.
Ferdinando Benito Attilio ValenteVascular Surgery Department, IRCCS H. San Raffaele, Milan, Italy.
Stefano BarcoDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There are limited data on functional and patient-reported outcomes after acute upper-extremity deep vein thrombosis (UEDVT) caused by compression syndromes. Objectives: This study examined patient-reported functional impairment, quality of life, and treatment satisfaction after UEDVT. Methods: We did a retrospective multicenter cohort study of patients with confirmed UEDVT due to compression syndromes not related to central lines. Patients were included at 5 centers in 4 countries and completed a standardized patient-reported outcome survey. The primary outcome was upper-limb function measured via the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) score (range, 0-100; higher scores indicate worse function) during follow-up. Quality of life was assessed using a Visual Analogue Scale. Additional outcomes included persistent symptoms, treatment satisfaction, mental health impact, and perception of unmet needs. Results: We included 82 patients (median age, 38 years; Q1-Q3, 26-48 years); 44% were women. All patients received anticoagulation, and 66% underwent catheter-directed therapy. First-rib resection was performed in 24% of patients. After a median follow-up of 16 months, 63% reported ≥1 persistent symptom, most commonly swelling (30%) and heaviness (29%). The median QuickDASH score was 8 (Q1-Q3, 2-20), indicating mild overall disability. QuickDASH correlated negatively with quality of life (Spearman ρ = -0.82; Conclusion: UEDVT can have lasting functional and psychosocial effects. Patient-reported outcomes reveal a burden that is not captured by traditional clinical metrics and should be integrated into routine care as well in the setting of interventional trials.

Indexed as

outcome assessment (health care)postthrombotic syndromequality of lifeupper-extremity deep vein thrombosisvenous thromboembolism

Identifiers

PMID41704797
PMCPMC12907070

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.