Evidence map›Paper›PMID 41706050›Full record

Observational studyDiabetes care2026

Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study.

Rieneke van der Meer, Sofia Pazmino, Nele Steenackers, Amar van Laar, Maarten Sluis, Luna Tolenaars, Jonathan Rosen, Carmen Hurtado Del Pozo, Carel W le Roux, Jumana Al Kandari and 12 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Diabetes care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Rieneke van der MeerNederlandse Obesitas Kliniek, Huis ter Heide, the Netherlands.
Sofia PazminoClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Nele SteenackersClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Amar van LaarClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Maarten SluisNederlandse Obesitas Kliniek, The Hague, the Netherlands.
Luna TolenaarsDepartment of Surgery, St. Antoniusziekenhuis, Nieuwegein, the Netherlands.
Jonathan RosenBreakthrough T1D, New York, NY.
Carmen Hurtado Del PozoBreakthrough T1D, New York, NY.
Carel W le RouxDiabetes Complications Research Centre, University College Dublin, Dublin, Ireland.
Jumana Al KandariDAFNE unit, Department of Clinical Research and Clinical Trials, Dasman Diabetes Institute, Dasman, Kuwait.
Mohammad IrshadDAFNE unit, Department of Clinical Research and Clinical Trials, Dasman Diabetes Institute, Dasman, Kuwait.
Matthias LannooClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Ellen DeleusClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Bruno DillemansDepartment of Abdominal Surgery, AZ Sint Jan, Bruges, Belgium.
Yves Van NieuwenhoveDepartment of Gastrointestinal Surgery, Ghent University Hospital, Ghent, Belgium.
Arianne van BonDepartment of Endocrinology, Rijnstate Hospital/Vitalys Clinics, Arnhem, the Netherlands.
Eric HazebroekDepartment of Surgery, Rijnstate Hospital/Vitalys Clinics, Arnhem, the Netherlands.
Ebaa Al OzairiDAFNE unit, Department of Clinical Research and Clinical Trials, Dasman Diabetes Institute, Dasman, Kuwait.
Roel HoogmaNederlandse Obesitas Kliniek, The Hague, the Netherlands.
Chantal MathieuClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Ronald LiemNederlandse Obesitas Kliniek, The Hague, the Netherlands.
Bart Van der SchuerenClinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.ORCID 0000-0003-4754-784X

Funding

Breakthrough T1DEFPIAEuropean UnionInnovative Medicines Initiative 2 Joint Undertaking 875534Obesity Action CoalitionT1D Exchange
6 · The paper itself

Abstract

objectiveTo assess the effect of metabolic bariatric surgery (MBS) in people living with type 1 diabetes (T1D) and obesity. RESEARCH DESIGN AND

methodsFrom retrospective multicenter data, total weight loss, daily insulin requirement, HbA1c, and cardiometabolic parameters were assessed before and after surgery. Longitudinal models were used to identify response determinants.

resultsThis study included 162 people living with T1D and obesity. One year after surgery, mean total weight loss percentage was 29.7% (interquartile range [IQR] = 29.4, 30.3). Insulin requirements dropped from 0.75 (IQR = 0.58, 1.00) units/kg/day to 0.32 (IQR = 0.23, 0.43) units/kg/day (P < 0.001), and HbA1c dropped from 64.0 (IQR = 57.0, 74.0) mmol/mol to 60.0 (IQR = 53.4, 68.0) mmol/mol (P < 0.001). LDL, HDL, total cholesterol, and triglyceride levels significantly improved after surgery (P < 0.001). Greater total weight loss was associated with reduced insulin requirements, and higher baseline HbA1c was associated with poorer postsurgery glycemic control.

conclusionsMBS was associated with substantial metabolic improvement in people with T1D and obesity, in particular in those with high HbA1c and insulin need at baseline.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 1Glycemic ControlWeight LossAdultBlood GlucoseFemaleGlycated HemoglobinHumansInsulinMaleMiddle AgedObesityRetrospective StudiesBlood GlucoseGlycated HemoglobinInsulin

Identifiers

PMID41706050
PMCPMC13006809

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.